Evidence map›Paper›PMID 31164823›Full record

ArticleFrontiers in pharmacology2019

Sonodynamic Therapy With Anticancer Micelles and High-Intensity Focused Ultrasound in Treatment of Canine Cancer.

Yuki Horise, Masanori Maeda, Yoshiyuki Konishi, Jun Okamoto, Soko Ikuta, Yoshiharu Okamoto, Hiroshi Ishii, Shin Yoshizawa, Shinichiro Umemura, Tsuyoshi Ueyama and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. [Utilizing Sonodynamic Therapy-Induced Pyroptosis for Liver Cancer Therapy].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  3. Review
  4. Article
  5. A review of the development of histotripsy for extremity tumor ablation with a canine comparative oncology model to inform human treatments.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2023
    Review
  6. Review
  7. Review
  8. High-intensity focused ultrasound therapy for pancreatic cancer.Journal of medical ultrasonics (2001) · 2022
    Review
  9. Review
  10. Non-invasive cancer detection in canine urine throughFrontiers in veterinary science · 2022
    Article
  11. High intensity focused ultrasound for the treatment of solid tumors: a pilot study in canine cancer patients.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2022
    Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yuki HoriseInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan.
Masanori MaedaMakeWay Merger Company, Saitama, Japan.
Yoshiyuki KonishiInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan.
Jun OkamotoInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan.
Soko IkutaInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan.
Yoshiharu OkamotoFaculty of Agriculture, Tottori University, Tottori, Japan.
Hiroshi IshiiTokyo Animal Medical Center, Tokyo, Japan.
Shin YoshizawaDepartment of Communications Engineering, Tohoku University, Sendai, Japan.
Shinichiro UmemuraDepartment of Biomedical Engineering, Tohoku University, Sendai, Japan.
Tsuyoshi UeyamaMedical Business Department, DENSO Corporation, Nisshin, Japan.
Satoshi TamanoHealthcare Business Unit, Hitachi, Ltd, Tokyo, Japan.
Atsushi SofuniDepartment of Gastroenterology and Hepatology, Tokyo Medical University Hospital, Tokyo, Japan.
Kazuhisa TakemaePharmaceutical Division, Kowa Company, Ltd, Tokyo, Japan.
Ken MasamuneInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan.
Hiroshi IsekiInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan.
Nobuhiro NishiyamaPolymer Chemistry Division, Tokyo Institute of Technology, Meguro, Japan.
Kazunori KataokaDepartment of Materials Engineering, The University of Tokyo, Tokyo, Japan.
Yoshihiro MuragakiInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sonodynamic therapy (SDT) is a minimally invasive anticancer therapy involving a chemical sonosensitizer and high-intensity focused ultrasound (HIFU). SDT enables the reduction of drug dose and HIFU irradiation power compared to those of conventional monotherapies. In our previous study, mouse models of colon and pancreatic cancer were used to confirm the effectiveness of SDT vs. drug-only or HIFU-only therapy. To validate its usefulness, we performed a clinical trial of SDT using an anticancer micelle (NC-6300) and our HIFU system in four pet dogs with spontaneous tumors, including chondrosarcoma, osteosarcoma, hepatocellular cancer, and prostate cancer. The fact that no adverse events were observed, suggests the usefulness of SDT.

Indexed as

anticancer micellesdrug delivery systemhigh-intensity focused ultrasoundminimally invasivesonodynamic therapy

Identifiers

PMID31164823
PMCPMC6536587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.