Evidence map›Paper›PMID 31164624›Full record

ArticleMethods and protocols2019

Induction of a Th17 Phenotype in Human Skin-A Mimic of Dermal Inflammatory Diseases.

Sara M Garrett, Qihong Zhao, Carol Feghali-Bostwick

Open access · goldAbstract read
In one paragraph

Article in Methods and protocols, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sara M GarrettDepartment of Medicine, Division of Rheumatology, Medical University of South Carolina (MUSC), Charleston, SC 29425, USA. smg21@musc.edu.ORCID 0000-0001-9220-0947
Qihong ZhaoBristol-Myers Squibb, Princeton, NJ 08543, USA. qihong.zhao@bms.com.
Carol Feghali-BostwickDepartment of Medicine, Division of Rheumatology, Medical University of South Carolina (MUSC), Charleston, SC 29425, USA. feghalib@musc.edu.ORCID 0000-0002-6750-6407
Medical University of South Carolina · USBristol-Myers Squibb (United States) · US

Funding

Scleroderma Twin Study and analysis of Estrogen in patients with dcSScK24AR060297 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FEGHALI-BOSTWICK, CAROL A. · 2013 to 2025
$1.4M
Bristol-Myers Squibb N/ANIAMS NIH HHS K24 AR060297NIH HHS 5T32AR050958NIH HHS K24AR060297
6 · The paper itself

Abstract

Th17 cells are a subset of effector T helper cells that produce interleukin (IL)-17A, IL-17F, IL-22, and IL-26, which can promote tissue inflammation and contribute to the pathogenesis of rheumatic, fibrosing, and other diseases. Research into these diseases is often limited by a lack of an animal model that closely mimics human disease and the paucity of patient clinical tissues. Therefore, the development of relevant experimental models is crucial. Three media formulations of Th17-skewing cocktail (CT) were evaluated for the ability to induce a Th17 signature in an

Indexed as

ex vivoIL-17skinTh17 cytokine

Identifiers

PMID31164624
PMCPMC6632176
OpenAlexW2948135066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.