Evidence map›Paper›PMID 31164574›Full record

ArticleMethods and protocols2018

Improved Detection and Fragmentation of Disulphide-Linked Peptides.

Evelyne Maes, Stefan Clerens, Jolon M Dyer, Santanu Deb-Choudhury

Open access · goldAbstract read
In one paragraph

Article in Methods and protocols, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Evelyne MaesFood & Bio-Based Products, AgResearch Ltd., 1365 Springs Road, Lincoln 7674, New Zealand. evelyne.maes@agresearch.co.nz.
Stefan ClerensFood & Bio-Based Products, AgResearch Ltd., 1365 Springs Road, Lincoln 7674, New Zealand. stefan.clerens@agresearch.co.nz.
Jolon M DyerFood & Bio-Based Products, AgResearch Ltd., 1365 Springs Road, Lincoln 7674, New Zealand. Jolon.dyer@agresearch.co.nz.
Santanu Deb-ChoudhuryFood & Bio-Based Products, AgResearch Ltd., 1365 Springs Road, Lincoln 7674, New Zealand. Santanu.deb-choudhury@agresearch.co.nz.
AgResearch · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Characterisation of peptides containing intact disulphide bonds (DSBs) via mass spectrometry is challenging. Our study demonstrates that the addition of aniline to alpha-cyano-4-hydroxycinnamic acid improves detection and fragmentation of complex DSB peptides by matrix-assisted laser desorption/ionization, tandem time-of-flight mass spectrometry (MALDI-TOF-TOF MS). This improved assignment will be a significant new tool when a simple screening to confirm the DSB existence is required.

Indexed as

anilinedisulphide bondsMALDI-TOF/TOF MSproof-of-existence

Identifiers

PMID31164574
PMCPMC6481087
OpenAlexW2889896246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.