Evidence map›Paper›PMID 31164572›Full record

ArticleMethods and protocols2018

Molecular Analysis of PKU-Associated PAH Mutations: A Fast and Simple Genotyping Test.

Manuela Tolve, Cristiana Artiola, Amelia Pasquali, Teresa Giovanniello, Sirio D'Amici, Antonio Angeloni, Antonio Pizzuti, Claudia Carducci, Vincenzo Leuzzi, Carla Carducci

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods and protocols, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Manuela TolveDepartment of Experimental Medicine, Sapienza University, 00185 Rome, Italy. m.tolve@policlinicoumberto1.it.
Cristiana ArtiolaDepartment of Experimental Medicine, Sapienza University, 00185 Rome, Italy. c.artiola@policlinicoumberto1.it.
Amelia PasqualiDepartment of Experimental Medicine, Sapienza University, 00185 Rome, Italy. amelia.pasquali@uniroma1.it.
Teresa GiovannielloDepartment of Experimental Medicine, Sapienza University, 00185 Rome, Italy. t.giovanniello@policlinicoumberto1.it.
Sirio D'AmiciDepartment of Experimental Medicine, Sapienza University, 00185 Rome, Italy. sirio.damici@uniroma1.it.
Antonio AngeloniDepartment of Experimental Medicine, Sapienza University, 00185 Rome, Italy. antonio.angeloni@uniroma1.it.
Antonio PizzutiDepartment of Experimental Medicine, Sapienza University, 00185 Rome, Italy. antonio.pizzuti@uniroma1.it.
Claudia CarducciDepartment of Experimental Medicine, Sapienza University, 00185 Rome, Italy. claudia.carducci@uniroma1.it.
Vincenzo LeuzziDepartment of Human Neuroscience, Child Neurology and Psychiatry Sapienza University, 00185 Rome, Italy. vincenzo.leuzzi@uniroma1.it.
Carla CarducciDepartment of Experimental Medicine, Sapienza University, 00185 Rome, Italy. carla.carducci@uniroma1.it.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal screening for phenylketonuria (PKU, OMIM: 261600) was introduced at the end of the 1960s. We developed a rapid and simple molecular test for the most frequent phenylalanine hydroxylase (

Indexed as

phenylalanine hydroxylase deficiencyphenylketonuriaPKU mutation analysisPKU screening

Identifiers

PMID31164572
PMCPMC6481045
OpenAlexW2885671034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.