ArticlemBio2019
Antibody Treatment against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia.
Open access · goldAbstract read
In one paragraph
Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
- Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH.Nature communications · 2026Article
- Inhaled Angiopoietin-Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- NETs accelerate aortic valve calcification by promoting M1 macrophage polarization through the TLR9 signaling pathway.Molecular and cellular biochemistry · 2025Article
- Physical Activity, Exerkines, and Their Role in Cancer Cachexia.International journal of molecular sciences · 2025Review
- ANGPTL4: A Comprehensive Review of 25 Years of Research.Cancers · 2025Review
- Microcella aerolata GA224 exhibits preventive potential against Streptococcus pneumoniae infection via the gut-lung axis.World journal of microbiology & biotechnology · 2025Article
- Article
- Emerging roles of angiopoietin‑like 4 in human tumors (Review).International journal of oncology · 2025Review
- ANGPTL4-the Link Binding Lipid Metabolism and Inflammation.Current medicinal chemistry · 2025Review
- Bone-protective effects of neutralizing angiopoietin-like protein 4 monoclonal antibody in rheumatoid arthritis.Molecular therapy : the journal of the American Society of Gene Therapy · 2024Article
- Article
- A nomogram based on the expression level of angiopoietin-like 4 to predict the severity of community-acquired pneumonia.BMC infectious diseases · 2023Article
- The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therapy.eLife · 2023Article
- Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity.Critical care explorations · 2023Article
- Dual roles of ANGPTL4 in multiple inflammatory responses in stomatitis mice.Molecular biology reports · 2022Article
- Role of Neuropilin 1 in COVID-19 Patients with Acute Ischemic Stroke.Biomedicines · 2022Review
- Pericyte-like cells undergo transcriptional reprogramming and distinct functional adaptations in acute lung injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Expression of angiopoietin-like 4 fibrinogen-like domain (cANGPTL4) increases risk of brain metastases in women with breast cancer.Oncotarget · 2020Article
- Neutrophil extracellular traps induced by IL-8 aggravate atherosclerosis via activation NF-κB signaling in macrophages.Cell cycle (Georgetown, Tex.) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 6 institutions in 4 countries.
Liang LiInstitute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Nanshan, Shenzhen, China liang.li@siat.ac.cn nstan@ntu.edu.sg.
Benjamin Jie Wei FooSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Ka Wai KwokSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Noriho SakamotoDepartment of Respiratory Medicine, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Hiroshi MukaeDepartment of Respiratory Medicine, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Koichi IzumikawaDepartment of Respiratory Medicine, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Stéphane MandardINSERM LNC, UMR1231, Dijon, France.
Jean-Pierre QuenotINSERM LNC, UMR1231, Dijon, France.
Laurent LagrostINSERM LNC, UMR1231, Dijon, France.
Wooi Keong TehSingapore Centre for Environmental Life Sciences Engineering (SCELSE), Interdisciplinary Graduate School, Nanyang Technological University, Singapore, Singapore.ORCID 0000-0001-9052-6644
Gurjeet Singh KohliSingapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, Singapore, Singapore.
Pengcheng ZhuSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Hyungwon ChoiSaw Swee Hock School of Public Health, National University of Singapore, Singapore.
Martin Lindsay BuistDepartment of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore.
Ju Ee SeetDepartment of Pathology, National University Hospital, Singapore, Singapore.
Liang YangSchool of Medicine, Southern University of Science and Technology, Shenzhen, China.ORCID 0000-0002-2362-0128
Fang HeInstitute of Preventive Veterinary Medicine, and Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China.
Vincent Tak Kwong ChowHost and Pathogen Interactivity Laboratory, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Nguan Soon TanSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore liang.li@siat.ac.cn nstan@ntu.edu.sg.ORCID 0000-0003-0136-7341
Nanyang Technological University · SGInserm · FRNagasaki University · JPNational University of Singapore · SGNational University Hospital · SGZhejiang University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Secondary bacterial lung infection by
Indexed as
Angiopoietin-Like Protein 4AnimalsAnti-Bacterial AgentsAntibodiesCoinfectionDisease Models, AnimalFemaleInflammationLungMiceMice, Inbred BALB CPneumonia, PneumococcalPulmonary EdemaStreptococcus pneumoniaeAngiopoietin-Like Protein 4Angptl4 protein, mouseAnti-Bacterial AgentsAntibodiesANGPTL4antibiotic resistancehost-directed immunotherapeuticssecondary bacterial pneumoniavascular permeability
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.