ArticleCirculation. Cardiovascular quality and outcomes2019
Clinic-Based Strategies to Reach United States Million Hearts 2022 Blood Pressure Control Goals.
Article in Circulation. Cardiovascular quality and outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05347823 (Study of Adherence to Antihypertensive Drugs and Statins in the Population of Subjects With Hypertension Followed at SIIA Centers, Using an Innovative Monitoring Based on Hair Analysis), which is not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study of Adherence to Antihypertensive Drugs and Statins in the Population of Subjects With Hypertension Followed at SIIA Centers, Using an Innovative Monitoring Based on Hair Analysis
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Effectiveness and Cost-Effectiveness of Team-Based Care for Hypertension: A Meta-Analysis and Simulation Study.Hypertension (Dallas, Tex. : 1979) · 2023Pooled it
- Improvement in Blood Pressure Control in Safety Net Clinics Receiving 2 Versions of a Scalable Quality Improvement Intervention: BP MAP A Pragmatic Cluster Randomized Trial.Journal of the American Heart Association · 2023Trial
- Analysis of Therapeutic Inertia and Race and Ethnicity in the Systolic Blood Pressure Intervention Trial: A Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2022Trial
- Blood Pressure Medication Side Effect Symptoms and Patient Treatment Satisfaction and Adherence.Journal of the American Board of Family Medicine : JABFMTrial
- Healthcare insurance status and hypertension control before and after the Affordable Care Act.American journal of hypertension · 2026Article
- Medicaid coverage for fixed-dose combination antihypertensive medications - fifty states and Washington, D.C., 2022.Journal of human hypertension · 2026Article
- Factors Associated with Treatment Intensification for Uncontrolled Hypertension in a US Health System.Journal of general internal medicine · 2026Article
- Bridging evidence and practice: multi-method evaluation of implementation fidelity of a multilevel hypertension intervention in a federally qualified health center.Frontiers in health services · 2026Article
- Leading Causes of Death Among US Adults With and Without Hypertension: Data From the REGARDS Study.American journal of hypertension · 2025Article
- Implementing Equitable Hypertension Care Using a Remote Patient Monitoring Program: A Mixed Methods Study.JACC. Advances · 2025Article
- Implementing remote patient monitoring to improve hypertension control in a primary care network: Rationale and design of the monitor-BP Cluster Randomized Trial.American heart journal · 2025Article
- Comparing 3 Evidence-Based Strategies to Reduce Cardiovascular Disease Burden: An Individual-Based Cardiometabolic Policy Simulation.Journal of the American Heart Association · 2025Article
- Cost-Effectiveness of a Polypill for Cardiovascular Disease Prevention in an Underserved Population.JAMA cardiology · 2025Article
- Trends in Blood Pressure Control among US Adults With Hypertension, 2013-2014 to 2021-2023.American journal of hypertension · 2025Article
- Achieving Equity in Hypertension: A Review of Current Efforts by the American Heart Association.Hypertension (Dallas, Tex. : 1979) · 2024Review
- Trends of Antihypertensive Prescription Among US Adults From 2010 to 2019 and Changes Following Treatment Guidelines: Analysis of Multicenter Electronic Health Records.Journal of the American Heart Association · 2024Article
- Managing Hypertension in Older Adults.Current hypertension reports · 2024Review
- Association Between Self-Reported Medication Adherence and Therapeutic Inertia in Hypertension: A Secondary Analysis of SPRINT (Systolic Blood Pressure Intervention Trial).Journal of the American Heart Association · 2024Article
- Effectiveness of Hypertension Management Strategies in SPRINT-Eligible US Adults: A Simulation Study.Journal of the American Heart Association · 2024Article
- Design and Implementation of an Electronic Health Record-Integrated Hypertension Management Application.Journal of the American Heart Association · 2024Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundThe Centers for Disease Control and Prevention's Million Hearts initiative includes an ambitious ≥80% blood pressure control goal in US adults with hypertension by 2022. We used the validated Blood Pressure Control Model to quantify changes in clinic-based hypertension management processes needed to attain ≥80% blood pressure control. METHODS AND
resultsThe Blood Pressure Control Model simulates patient blood pressures weekly using 3 key modifiable hypertension management processes: office visit frequency, clinician treatment intensification given uncontrolled blood pressure, and continued antihypertensive medication use (medication adherence rate). We compared blood pressure control rates (using the Seventh Joint National Committee on hypertension targets) achieved over 4 years between usual care and the best-observed values for management processes identified from the literature (1-week return visit interval, 20%-44% intensification rate, and 76% adherence rate). We determined the management process values needed to achieve ≥80% blood pressure control in US adults. In adults with uncontrolled blood pressure, usual care achieved 45.6% control (95% uncertainty interval, 39.6%-52.5%) and literature-based best-observed values achieved 79.7% control (95% uncertainty interval, 79.3%-80.1%) over 4 years. Increasing treatment intensification rates to 62% of office visits with an uncontrolled blood pressure resulted in ≥80% blood pressure control, even when the return visit interval and adherence remained at usual care values. Improving to best-observed values for all 3 management processes would achieve 78.1% blood pressure control in the overall US population with hypertension, approaching the ≥80% Million Hearts 2022 goal.
conclusionsAchieving the Million Hearts blood pressure control goal by 2022 will require simultaneously increasing visit frequency, overcoming therapeutic inertia, and improving patient medication adherence. As the relative importance of each of these 3 processes will depend on local characteristics, simulation models like the Blood Pressure Control Model can help local healthcare systems tailor strategies to reach local and national benchmarks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.