Evidence map›Paper›PMID 31163975›Full record

ArticleAIDS care2020

Perceived barriers to pre-exposure prophylaxis use and the role of syndemic factors among female sex workers in the Mexico-United States border region:

Jennifer P Jain, Steffanie A Strathdee, Thomas L Patterson, Shirley J Semple, Alicia Harvey-Vera, Carlos Magis-Rodríguez, Gustavo Martinez, Heather A Pines

Abstract read
In one paragraph

Article in AIDS care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer P JainDepartment of Medicine, University of California, San Diego, CA, USA.ORCID 0000-0002-6339-1649
Steffanie A StrathdeeDepartment of Medicine, University of California, San Diego, CA, USA.ORCID 0000-0002-7724-691X
Thomas L PattersonDepartment of Psychiatry, University of California, San Diego, CA, USA.ORCID 0000-0003-2311-6164
Shirley J SempleDepartment of Psychiatry, University of California, San Diego, CA, USA.
Alicia Harvey-VeraDepartment of Medicine, University of California, San Diego, CA, USA.ORCID 0000-0002-8708-8169
Carlos Magis-RodríguezMinistry of Health, Centro Nacional para la Prevención del VIH/SIDA (CENSIDA), Mexico City, Mexico.ORCID 0000-0001-5481-1253
Gustavo MartinezFederación Mexicana de Asociaciones Privadas, Ciudad Juarez, Mexico.
Heather A PinesDepartment of Medicine, University of California, San Diego, CA, USA.ORCID 0000-0002-7173-1981

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Mitchell Smith · 1994 to 2026
$78.4M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
Texting intervention to sustain HIV prevention in women in high-drug-use contextsR01DA039071 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PATTERSON, THOMAS L. · 2015 to 2019
$3.3M
Sexual Networks and HIV Transmission Clusters among Substance Using MSMK01DA040543 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PINES, HEATHER ALISA · 2015 to 2019
$901k
NCATS NIH HHS UL1 TR001442NIAID NIH HHS P30 AI036214NIDA NIH HHS K01 DA040543NIDA NIH HHS R01 DA039071NIDA NIH HHS T32 DA023356
6 · The paper itself

Abstract

Female sex workers (FSWs) experience syndemic factors (e.g., polydrug use, hazardous alcohol consumption, client-perpetrated violence, depression, and sexually transmitted infections) that often heighten vulnerability to HIV and limit healthcare utilization. We hypothesized that syndemic factors will limit FSWs' uptake of pre-exposure prophylaxis (PrEP). From 2016 to 2017, 295 HIV-negative FSWs were enrolled in a behavioral HIV prevention trial in Tijuana and Ciudad Juarez, Mexico, underwent STI testing, and completed surveys on syndemic factors and perceived barriers to PrEP use. Syndemic scores (0-5) were calculated by summing syndemic factors. Latent class analysis (LCA) was used to identify homogeneous classes with respect to perceived barriers to PrEP use. We identified four classes: (1) perceived healthcare access barriers (8.3%), (2) perceived financial barriers (18.7%), (3) high level of perceived barriers (19.9%), and (4) low level of perceived barriers (53.0%) to PrEP use. Those experiencing three (adjusted odds ratio [aOR] = 3.63, 95% confidence interval [CI] = 1.24-10.67) and four or five (aOR = 6.30, 95% CI = 1.70-23.35) syndemic factors had a higher odds of membership in the class characterized by a high level of perceived barriers than in the class characterized by a low level of perceived barriers. Addressing syndemic factors may maximize PrEP's impact among FSWs along Mexico's northern border.

Indexed as

Pre-Exposure ProphylaxisAdultAlcohol-Related DisordersFemaleHealth Services AccessibilityHIV InfectionsHumansLatent Class AnalysisMexicoPatient Acceptance of Health CarePrevalenceSex WorkersSyndemicUnited Statesfemale sex workersHIVlatent class analysisMexicopre-exposure prophylaxissyndemic theory

Identifiers

PMID31163975
PMCPMC6891112

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.