Evidence map›Paper›PMID 31163674›Full record

ArticleAntibiotics (Basel, Switzerland)2019

Size and Flexibility Define the Inhibition of the H3N2 Influenza Endonuclease Enzyme by Calix[n]arenes.

Yannick Tauran, José Pedro Cerón-Carrasco, Moez Rhimi, Florent Perret, Beomjoon Kim, Dominique Collard, Anthony W Coleman, Horacio Pérez-Sánchez

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yannick TauranLaboratoire Multimatériaux et Interfaces CNRS UMR 5615, Université Lyon 1, 69622 Villeurbanne, France. yannick.tauran@univ-lyon1.fr.ORCID 0000-0002-0706-7799
José Pedro Cerón-CarrascoBioinformatics and High Performance Computing (BIO-HPC) Research Group, Universidad Católica de Murcia (UCAM), 30107 Murcia, Spain. jpceron@ucam.edu.ORCID 0000-0003-0668-9227
Moez RhimiInstitut National de la Recherche Agronomique (INRA), UMR 1319 Micalis, F-78350 Jouy-en-Josas, France. moez.rhimi@jouy.inra.fr.
Florent PerretInstitut de Chimie et Biochimie Moléculaires et Supramoléculaires, CNRS UMR 5246, Université Lyon 1, 69622 Villeurbanne, France. florent.perret@univ-lyon1.fr.ORCID 0000-0003-1413-6374
Beomjoon KimLaboratory for Integrated Micro-Mechatronic Systems (LIMMS)/CNRS-IIS UMI 2820, Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan. bjoonkim@iis.u-tokyo.ac.jp.ORCID 0000-0001-9565-299X
Dominique CollardUniversité Lille, CNRS, Centrale Lille, Institut Supérieur de l'Electronique et du Numérique (ISEN), University Valenciennes, UMR 8520-IEMN, F59000 Lille, France. collard@iis.u-tokyo.ac.jp.
Anthony W ColemanLaboratoire Multimatériaux et Interfaces CNRS UMR 5615, Université Lyon 1, 69622 Villeurbanne, France. anthony.coleman@univ-lyon1.fr.
Horacio Pérez-SánchezBioinformatics and High Performance Computing (BIO-HPC) Research Group, Universidad Católica de Murcia (UCAM), 30107 Murcia, Spain. hperez@ucam.edu.ORCID 0000-0003-4468-7898

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España CTQ2017-87974-R
6 · The paper itself

Abstract

Inhibition of H3N2 influenza PA endonuclease activity by a panel of anionic calix[n]arenes and β-cyclodextrin sulfate has been studied. The joint experimental and theoretical results reveal that the larger, more flexible and highly water-soluble sulfonato-calix[n]arenes have high inhibitory activity, with para-sulfonato-calix[8]arene, SC8, having an IC

Indexed as

anti-viral activitycalix[n]areneendonucleaseenzyme inhibitorsH3N2 virusmolecular docking

Identifiers

PMID31163674
PMCPMC6627454

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.