Evidence map›Paper›PMID 31163628›Full record

ArticleDentistry journal2019

Spectrophotometric Determination of the Aggregation Activity of Platelets in Platelet-Rich Plasma for Better Quality Control.

Tetsuhiro Tsujino, Kazushige Isobe, Hideo Kawabata, Hachidai Aizawa, Sadahiro Yamaguchi, Yutaka Kitamura, Hideo Masuki, Taisuke Watanabe, Hajime Okudera, Koh Nakata and 1 more

Open access · goldAbstract read
In one paragraph

Article in Dentistry journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Tetsuhiro TsujinoTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan. tetsudds@gmail.com.
Kazushige IsobeTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan. kaz-iso@tc4.so-net.ne.jp.
Hideo KawabataTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan. hidei@eos.ocn.ne.jp.
Hachidai AizawaTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan. sarusaru@mx6.mesh.ne.jp.
Sadahiro YamaguchiTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan. y-sada@mwd.biglobe.ne.jp.
Yutaka KitamuraTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan. shinshu-osic@mbn.nifty.com.
Hideo MasukiTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan. hideomasuki@gmail.com.
Taisuke WatanabeTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan. watatai@mui.biglobe.ne.jp.
Hajime OkuderaTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan. okudera@carrot.ocn.ne.jp.
Koh NakataBioscience Medical Research Center, Niigata University Medical and Dental Hospital, Niigata 951-8520, Japan. radical@med.niigata-u.ac.jp.
Tomoyuki KawaseDivision of Oral Bioengineering, Institute of Medicine and Dentistry, Niigata University, Niigata 951-8514, Japan. kawase@dent.niigata-u.ac.jp.ORCID 0000-0003-4160-396X
Tokyo Dental College · JPNiigata University · JPNiigata University Medical and Dental Hospital · JP

Funding

Japan Society for the Promotion of Science 18K09595
6 · The paper itself

Abstract

Although platelet-rich plasma (PRP) is now widely used in regenerative medicine and dentistry, contradictory clinical outcomes have often been obtained. To minimize such differences and to obtain high quality evidence from clinical studies, the PRP preparation protocol needs to be standardized. In addition, emphasis must be placed on quality control. Following our previous spectrophotometric method of platelet counting, in this study, another simple and convenient spectrophotometric method to determine platelet aggregation activity has been developed. Citrated blood samples were collected from healthy donors and used. After centrifugation twice, platelets were suspended in phosphate buffered saline (PBS) and adenosine diphosphate (ADP)-induced aggregation was determined using a spectrophotometer at 615 nm. For validation, platelets pretreated with aspirin, an antiplatelet agent, or hydrogen peroxide (H

Indexed as

aggregationplatelet-rich plasmaplateletsquality assurancespectrophotometer

Identifiers

PMID31163628
PMCPMC6631196
OpenAlexW2947518262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.