Evidence map›Paper›PMID 31162983›Full record

ReviewExpert opinion on drug metabolism & toxicology2019

Pharmacogenetics of alcohol use disorder treatments: an update.

Emily E Hartwell, Henry R Kranzler

Abstract readReview
In one paragraph

Review in Expert opinion on drug metabolism & toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emily E Hartwella Mental Illness Research, Education and Clinical Center , Crescenz VAMC , Philadelphia , PA , USA.
Henry R Kranzlera Mental Illness Research, Education and Clinical Center , Crescenz VAMC , Philadelphia , PA , USA.

Funding

Pharmacogenetic Analysis of Topiramate Treatment of AUDR01AA023192 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI KRANZLER, HENRY RICHARD · 2014 to 2018
$2.7M
2/2 Pharmacogenetic Treatment for AlcoholismR01AA021164 · NIAAA · UNIVERSITY OF PENNSYLVANIA · PI KRANZLER, HENRY RICHARD, PETTINATI, HELEN M · 2012 to 2016
$2.1M
NIAAA NIH HHS R01 AA021164NIAAA NIH HHS R01 AA023192
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PharmacogeneticsAlcohol DeterrentsAlcoholismHumansOff-Label UsePrecision MedicineAlcohol DeterrentsAlcohol use disordergenetic moderatorspharmacogeneticspharmacotherapyprecision medicine

Identifiers

PMID31162983
PMCPMC6614002

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.