Evidence map›Paper›PMID 31162977›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

The KCNE2 potassium channel β subunit is required for normal lung function and resilience to ischemia and reperfusion injury.

Leng Zhou, Clemens Köhncke, Zhaoyang Hu, Torsten K Roepke, Geoffrey W Abbott

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Kv7 Channels in Lung Diseases.Frontiers in physiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Leng ZhouDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Clemens KöhnckeExperimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Zhaoyang HuLaboratory of Anesthesiology and Critical Care Medicine, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, China.
Torsten K RoepkeExperimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Geoffrey W AbbottBioelectricity Laboratory, Department of Physiology and Biophysics, School of Medicine, University of California-Irvine, Irvine, California, USA.
Chengdu University · CNKlinikum Görlitz · DEMax Delbrück Center · DEUniversity of California, Irvine · USWest China Hospital of Sichuan University · CN

Funding

Ion Channel Transporter InteractionsR35GM130377 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Geoffrey W Abbott · 2019 to 2026
$4.0M
Ion channel-transporter interactionsR01GM115189 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI ABBOTT, GEOFFREY W · 2015 to 2018
$1.1M
NIGMS NIH HHS R01 GM115189NIGMS NIH HHS R35 GM130377
6 · The paper itself

Abstract

The KCNE2 single transmembrane-spanning voltage-gated potassium (K

Indexed as

AnimalsCytokinesFemaleGene Expression RegulationGerm-Line MutationInflammationKCNQ1 Potassium ChannelLung InjuryMiceMice, KnockoutPhosphorylationPotassium Channels, Voltage-GatedReperfusion InjuryShab Potassium ChannelsCytokinesKcnb1 protein, mouseKcne2 protein, mouseKCNQ1 Potassium ChannelKcnq1 protein, mousePotassium Channels, Voltage-GatedShab Potassium ChannelsepithelialK channelKCNQ1MiRP1pulmonary

Identifiers

PMID31162977
PMCPMC6704464
OpenAlexW2948340170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.