Evidence map›Paper›PMID 31162843›Full record

ArticleProteins2019

The crystal structure of Klebsiella pneumoniae FeoA reveals a site for protein-protein interactions.

Richard O Linkous, Alexandrea E Sestok, Aaron T Smith

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proteins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. The structure of the full catalytic cycle ofbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. The structure of Vibrio cholerae FeoC reveals conservation of the helix-turn-helix motif but not the cluster-binding domain.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Richard O LinkousDepartment of Chemistry and Biochemistry, University of Maryland, Baltimore, Maryland.
Alexandrea E SestokDepartment of Chemistry and Biochemistry, University of Maryland, Baltimore, Maryland.
Aaron T SmithDepartment of Chemistry and Biochemistry, University of Maryland, Baltimore, Maryland.ORCID 0000-0002-9332-8683
University of Maryland, Baltimore · US

Funding

Graduate Training at The Chemistry Biology InterfaceT32GM066706 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SELEY-RADTKE, KATHERINE L, SMITH, AARON T · 2004 to 2023
$3.3M
FeoA-based Regulation of Pathogenic Ferrous Iron AcquisitionR21DE027803 · NIDCR · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SMITH, AARON T · 2019 to 2020
$366k
NIDCR NIH HHS DE027803NIDCR NIH HHS R21 DE027803NIGMS NIH HHS GM066706NIGMS NIH HHS T32 GM066706
6 · The paper itself

Abstract

In order to establish infection, pathogenic bacteria must obtain essential nutrients such as iron. Under acidic and/or anaerobic conditions, most bacteria utilize the Feo system in order to acquire ferrous iron (Fe

Indexed as

Bacterial ProteinsCrystallography, X-RayIron-Binding ProteinsKlebsiella InfectionsKlebsiella pneumoniaeMolecular Docking SimulationProtein ConformationProtein Interaction Domains and MotifsProtein Interaction MapsBacterial ProteinsFeoA protein, Klebsiella pneumoniaeIron-Binding ProteinsFeoironprotein-protein interactionsSH3transport

Identifiers

PMID31162843
PMCPMC6779513
OpenAlexW2952665042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.