Evidence map›Paper›PMID 31162763›Full record

ArticleJournal of sleep research2020

Gender differences in clinical, laboratory and polysomnographic features of restless legs syndrome.

Evi Holzknecht, Margarethe Hochleitner, Gregor K Wenning, Birgit Högl, Ambra Stefani

Open access · hybridAbstract read
In one paragraph

Article in Journal of sleep research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  8. Residual periodic limb movement index after CPAP therapy is associated with hypoxemia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  9. Article
  10. Review
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  12. Sex-specific patterns of discomfort in patients with restless legs syndrome.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Evi HolzknechtDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-2078-7472
Margarethe HochleitnerGender Medicine Unit, Medical University of Innsbruck, Innsbruck, Austria.
Gregor K WenningDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Birgit HöglDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Ambra StefaniDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Innsbruck Medical University · AT

Funding

Austrian Science Fund FWF KLI 236
6 · The paper itself

Abstract

Restless legs syndrome is a common neurological disorder with a clear female predominance. This study aims to evaluate gender differences in clinical, laboratory and polysomnographic features in patients with restless legs syndrome. For this retrospective analysis, 42 women and 42 men from the Innsbruck RLS database matched by age and therapy were included. Demographic data as well as different severity scales (IRLS, RLS-6 and CGI) were evaluated. Laboratory parameters included several indicators of serum iron status. In all patients, polysomnography was performed according to the AASM guidelines, and periodic leg movements during sleep were scored according to the AASM criteria. IRLS, RLS-6 and CGI revealed more severe symptoms in women (IRLS median [range]: 17.5 [0-35] versus 13.5 [0-32], p = 0.028; RLS-6 median [range]: 18 [0-39] versus 12 [1-42], p = 0.014). Women had lower serum ferritin levels than men (median [range] in μg L

Indexed as

FemaleHumansMaleMiddle AgedPolysomnographyRestless Legs SyndromeRetrospective StudiesSex CharacteristicsPeriodic leg movements during sleeppolysomnographyRLS phenotypeRLS severity scalessymptoms manifestation

Identifiers

PMID31162763
PMCPMC7317508
OpenAlexW2948075732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.