ReviewActa paediatrica (Oslo, Norway : 1992)2019
Review of childhood pain highlights the role of negative stress.
Review in Acta paediatrica (Oslo, Norway : 1992), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- The effects of a dance intervention on somatic symptoms and emotional distress in adolescent girls: A randomized controlled trial.The Journal of international medical research · 2020Trial
- Preoperative Oral Tasipimidine in Dogs Undergoing Elective Ovariectomy: Anxiolysis, Handling Quality and Cardiovascular Effects.Veterinary sciences · 2026Article
- Effects of active action observation on cognitive, emotional, motor, and somatosensory outcomes in adolescents with juvenile idiopathic arthritis: a prospective exploratory case series.Frontiers in human neuroscience · 2026Article
- Early Predictors of School Absenteeism in First-Grade Children: A Multidimensional Longitudinal Study in Japan.Children (Basel, Switzerland) · 2025Article
- A Preliminary Study: Evaluation of Oral Trazodone as a Strategy to Reduce Anesthetic Requirements in Bitches Undergoing Ovariectomy.Animals : an open access journal from MDPI · 2025Article
- Expectations and Experiences of Internet-Based Therapy for Adolescents with TMD Pain.Journal of oral & facial pain and headache · 2022Article
- Interlinking alcohol intake, mental stress, psychotic experiences and job performance of higher institutions' graduates: A structural equation modelling.Journal of education and health promotion · 2022Article
- Development of the Help Overcoming Pain Early (HOPE) Programme Built on a Person-Centred Approach to Support School Nurses in the Care of Adolescents with Chronic Pain-A Feasibility Study.Children (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
aimRecurrent pain of unknown origin is a major problem in children. The aim of the present review was to examine the hypothesis of negative stress as an aetiology of recurrent pain from different aspects. METHODS AND
resultsEpidemiological studies, clinical experience and hormonal data give support for such a hypothesis. Negative stress as a tentative aetiology for recurrent pain is reviewed. Stress, muscular tension, the startle reaction and its tentative relation to pain is illuminated. Deviations of hormonal secretion supporting a stress aetiology are mentioned. The role of central sensitisation for recurrent pain is discussed. Possible aetiological implications of recurrent pain as a local symptom or a general disorder are presented. Brain changes due to stress are shortly reviewed. Stress and pain in the clinic are highlighted. The importance of biological, psychological and social factors, as well as genetic elements, is discussed.
conclusionStress elicits neurobiological mechanisms. They may lead to many neurophysiological deviances. Increase of muscle tension and neuromuscular excitability and enhanced startle reaction may be of importance for recurring pain. The identification of stress as a primary cause of recurrent pain can have huge implications for understanding signs and treatment in clinical practice.
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