ReviewCurrent aging science2019
An Overview of Neuromuscular Junction Aging Findings in Human and Animal Studies.
Review in Current aging science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Proteomics of aging: biomarkers for physiological systems and diseases.Frontiers in aging · 2026Review
- Equine grass sickness is associated with major abnormalities in the ultrastructure of skeletal neuromuscular junctions.Equine veterinary journal · 2025Article
- Molecular constraints of sarcopenia in the ageing muscle.Frontiers in aging · 2025Review
- How soon do metabolic alterations and oxidative distress precede the reduction of muscle mass and strength in Wistar rats in aging process?Biogerontology · 2024Article
- Disruption of Neuromuscular Junction Following Spinal Cord Injury and Motor Neuron Diseases.International journal of molecular sciences · 2024Review
- Sympathetic modulation of hindlimb muscle contractility is altered in aged rats.Scientific reports · 2023Article
- Review
- Profiling age-related muscle weakness and wasting: neuromuscular junction transmission as a driver of age-related physical decline.GeroScience · 2021Article
- Age Differences in Motor Recruitment Patterns of the Shoulder in Dynamic and Isometric Contractions. A Cross-Sectional Study.Journal of clinical medicine · 2021Article
- Motoneuron deafferentation and gliosis occur in association with neuromuscular regressive changes during ageing in mice.Journal of cachexia, sarcopenia and muscle · 2020Article
- The TOR Pathway at the Neuromuscular Junction: More Than a Metabolic Player?Frontiers in molecular neuroscience · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAging is a complex irreversible process that is not only related to an individual's genetic make-up but also to lifestyle choices and environmental exposures. Like every other structure in human body, the Neuromuscular Junction (NMJ) is not averse to aging.
objectivesThe prime objective is to analyse the microscopic and macroscopic changes at the NMJs with aging.
methodsFor the purpose of review we evaluated data from resources like Pubmed, Ovid, UCLA libraries and USC libraries.
resultsWe review various morphological, physiological, immunological, and biochemical changes in NMJs with aging and their management.
conclusionThe alterations in NMJs secondary to aging are inevitable. It is vital that neurologists clearly understand the pathophysiology of NMJ aging and differentiate between physiological and pathological effects of aging. With the current knowledge of science, the changes in NMJ aging can be better prevented rather than cured.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.