ArticleAmerican journal of respiratory and critical care medicine2019
BAL Cell Gene Expression in Severe Asthma Reveals Mechanisms of Severe Disease and Influences of Medications.
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Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
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Who cites it
36 citing papers in PubMed, 48 citations in OpenAlex.
- Transcriptomic profiling of pediatric asthma by diseases state and severity.Respiratory research · 2026Article
- Metabolic licensing at the dendritic cell-NK cells immune synapse in viral asthma exacerbations.Frontiers in immunology · 2026Review
- Unraveling the Molecular Complexity of Asthma: Insights from a Multicohort Transcriptome Study.American journal of respiratory cell and molecular biology · 2025Article
- Genomic crosstalk between carbachol, a muscarinic receptor agonist, and the long-acting βThe Journal of pharmacology and experimental therapeutics · 2025Article
- Epigenomic and proteomic analyses provide insights into early-life immune regulation and asthma development in infants.Nature communications · 2025Article
- Biologic Medications for Severe Asthma: Implications for Understanding Pathogenic Heterogeneity and Endotypes.Annual review of medicine · 2025Review
- Long-term alterations in lung epithelial cells after EL-RSV infection exacerbate allergic responses through IL-1β-induced pathways.Mucosal immunology · 2024Article
- Protein-Protein interactive networks identified in bronchoalveolar lavage of severe compared to nonsevere asthma.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2024Article
- Discovery of common molecular signatures and drug repurposing for COVID-19/Asthma comorbidity: ACE2 and multi-partite networks.Cell cycle (Georgetown, Tex.) · 2024Article
- Dissecting the Immune System through Gene Regulation.Advances in experimental medicine and biology · 2024Article
- Unveiling the Diagnostic Potential: A Comprehensive Review of Bronchoalveolar Lavage in Interstitial Lung Disease.Cureus · 2024Review
- Cytotoxic CD4Med (New York, N.Y.) · 2023Article
- Unraveling the link between PTBP1 and severe asthma through machine learning and association rule mining method.Scientific reports · 2023Article
- Epithelial CST1 Promotes Airway Eosinophilic Inflammation in Asthma via the AKT Signaling Pathway.Allergy, asthma & immunology research · 2023Article
- Classification of tuberculosis-related programmed cell death-related patient subgroups and associated immune cell profiling.Frontiers in immunology · 2023Article
- Determining asthma endotypes and outcomes: Complementing existing clinical practice with modern machine learning.Cell reports. Medicine · 2022Review
- T-cell responses in asthma exacerbations.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022Review
- Multi-Omics Profiling Approach to Asthma: An Evolving Paradigm.Journal of personalized medicine · 2022Review
- The horizon of pediatric cardiac critical care.Frontiers in pediatrics · 2022Review
- Challenges in severe asthma: Do we need new drugs or new biomarkers?Frontiers in medicine · 2022Review
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Authors and funding
20 authors at 10 institutions in 1 country.
Nathaniel WeathingtonDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Michael E O'BrienDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Josiah RadderDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Thomas C WhisenantDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California.
Eugene R BleeckerDivision of Genetics, Genomics and Precision Medicine, University of Arizona, Tucson, Arizona.
William W BusseDivision of Allergy, Pulmonary, and Critical Care Medicine, University of Wisconsin, Madison, Wisconsin.
Serpil C ErzurumLerner Research Institute, Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.
Benjamin GastonDivision of Pediatric Pulmonary, Allergy and Immunology, Case Western Reserve University and Rainbow Babies Children's Hospital, Cleveland, Ohio.
Annette T HastieSection on Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Nizar N JarjourDivision of Allergy, Pulmonary, and Critical Care Medicine, University of Wisconsin, Madison, Wisconsin.
Deborah A MeyersDivision of Genetics, Genomics and Precision Medicine, University of Arizona, Tucson, Arizona.
Jadranka MilosevicDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Wendy C MooreSection on Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest School of Medicine, Winston-Salem, North Carolina.
John R TedrowDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
John B TrudeauDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Hesper P WongDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Wei WuComputational Biology Department, Carnegie Mellon University, Pittsburgh, Pennsylvania.
Naftali KaminskiPulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut.
Sally E WenzelDivision of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Brian D ModenaDivision of Allergy, National Jewish Hospital, Denver, Colorado.ORCID 0000-0002-4406-8336
University of Pittsburgh · USUniversity of Arizona · USUniversity of Wisconsin–Madison · USWake Forest University · USCarnegie Mellon University · USCleveland Clinic Lerner College of Medicine · USJewish Hospital · USRainbow Babies & Children's Hospital · USScripps Research Institute · USYale University · US
Funding
University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9MUNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9MINSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5MTargeting pathological hyaluronan matricesP01HL103453 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI ERZURUM, SERPIL C. · 2011 to 2020
$26.8MProject 2 Impact of Innate and Adaptive Immunity At the Airway Epithelium in Severe AsthmaP01AI106684 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sally E Wenzel · 2015 to 2026
$18.9MSevere Asthma Research ProjectR01HL069174 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WENZEL, SALLY E · 2001 to 2010
$9.2MSevere Asthma From Respiratory InfectionsR01HL069116 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BUSSE, WILLIAM W. · 2001 to 2010
$7.6MGenotype-Phenotype Interactions in Severe AsthmaR01HL069167 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BLEECKER, EUGENE ROLAND · 2001 to 2010
$5.5MAirway redox biochemistry as a deteriminant of asthma phenotype during adolescen*U10HL109250 · NHLBI · UNIVERSITY OF VIRGINIA · PI ERZURUM, SERPIL C., GASTON, BENJAMIN · 2011 to 2016
$4.2MLinking Genetics, Genomics and Phenomics to Better Understand Asthma SeverityRC2HL101487 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BLEECKER, EUGENE ROLAND, KAMINSKI, NAFTALI · 2009 to 2010
$3.5MCellular regulation of the IL-22 receptor and its importance in lung immunity.K08HL126135 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WEATHINGTON, NATHANIEL M · 2015 to 2019
$766kGenomic Analysis of Epithelial Growth and Repair Mechanisms in Aspirin Exacerbated Respiratory DiseaseK23HL144418 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MODENA, BRIAN DAVID · 2018 to 2021
$502kNCATS NIH HHS UL1 TR002373NCRR NIH HHS UL1 RR024153NCRR NIH HHS UL1 RR025011NHLBI NIH HHS K08 HL126135NHLBI NIH HHS K23 HL144418NHLBI NIH HHS P01 HL103453NHLBI NIH HHS R01 HL069116NHLBI NIH HHS R01 HL069167NHLBI NIH HHS R01 HL069174NHLBI NIH HHS R03 HL144888NHLBI NIH HHS RC2 HL101487NHLBI NIH HHS U10 HL109250NIAID NIH HHS P01 AI106684
Abstract
PubMed holds no abstract for this paper.
Indexed as
Adrenergic beta-AgonistsAdultAsthmaBronchoalveolar Lavage FluidCase-Control StudiesCyclic AMPEosinophilsEpithelial CellsFemaleGene ExpressionHumansIn Vitro TechniquesLymphocytesMacrophages, AlveolarMaleNeutrophilsAdrenergic beta-AgonistsCyclic AMPasthmabronchoalveolar lavagegene expressiongeneticsβ-agonist
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.