Evidence map›Paper›PMID 31161900›Full record

ArticleCancer biology & therapy2019

LINC00958 regulated miR-627-5p/YBX2 axis to facilitate cell proliferation and migration in oral squamous cell carcinoma.

Fuyang Chen, Mingyue Liu, Yixiu Yu, Yanyan Sun, Jihe Li, Weiping Hu, Xiaofeng Wang, Dongxia Tong

Open access · bronzeAbstract read
In one paragraph

Article in Cancer biology & therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 51 citations in OpenAlex.

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  6. mRNA mCellular and molecular life sciences : CMLS · 2022
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  20. [Expression and effect of microRNA-627 in human hypertrophic scar].Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Fuyang ChenDepartment of Stomatology, The Second Affiliated Hospital of Harbin Medical University , Harbin , China.
Mingyue LiuDepartment of Prosthodontics, The Second Affiliated Hospital of Harbin Medical University , Harbin , China.
Yixiu YuDepartment of Stomatology, The First Affiliated Hospital of Harbin Medical University , Harbin , China.
Yanyan SunDepartment of Prosthodontics, Xuzhou Stomatological Hospital , Xuzhou , China.
Jihe LiDepartment of Cardiology, The First Affiliated Hospital of Harbin Medical University , Harbin , China.
Weiping HuDepartment of Prosthodontics, The Second Affiliated Hospital of Harbin Medical University , Harbin , China.
Xiaofeng WangDepartment of Stomatology, The Second Affiliated Hospital of Harbin Medical University , Harbin , China.
Dongxia TongDepartment of Hematology, First Hospital of Harbin Medical University , Harbin , China.
Harbin Medical University · CNSecond Affiliated Hospital of Harbin Medical University · CNFirst Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC), the subtype of head and neck cancers, is notorious for its high incidence and death rate. The role of long non-coding RNAs (lncRNAs) is discovered to be significant for the canceration and cancer progression. Long intergenic non-protein coding RNA 958 (LINC00958) is discovered as a carcinogene in multiple cancers, such as gastric cancer, pancreatic cancer, and glioma, but there has been no report about how LINC00958 functions in OSCC. The objective of our study is to unfold function and mechanism investigation on LINC00958 in OSCC. First, TCGA database showed the upregulation and prognostic significance of LINC00958 in head and neck squamous carcinoma. Then, we discovered in OSCC clinical samples that LINC00958 presented high expression and predicted poor prognosis. Also, LINC00958 was elevated in OSCC cells.

Indexed as

RNA, Long Noncoding3' Untranslated RegionsApoptosisCarcinoma, Squamous CellCell Line, TumorCell MovementCell ProliferationEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansMicroRNAsMouth NeoplasmsRNA-Binding ProteinsRNA Interference3' Untranslated RegionsMicroRNAsMIRN627 microRNA, humanRNA-Binding ProteinsRNA, Long NoncodingYBX2 protein, humanLINC00958miR-627-5pOSCCYBX2

Identifiers

PMID31161900
PMCPMC6741574
OpenAlexW2948423997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.