ArticleJournal of applied physiology (Bethesda, Md. : 1985)2019
Impaired diaphragm resistance vessel vasodilation with prolonged mechanical ventilation.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Feasibility of the Manual Diaphragm Release Technique in Neurocritical Patients on Mechanical Ventilation: A Pilot Randomized Controlled Trial.Medical sciences (Basel, Switzerland) · 2025Trial
- Effects of elevated positive end-expiratory pressure on diaphragmatic blood flow and vascular resistance during mechanical ventilation.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Trial
- The Role of Nitric Oxide in Regulating Microvascular Oxygen Pressure During Diaphragm Contraction in Rats.Advances in experimental medicine and biology · 2026Article
- Article
- Effects of aging on diaphragm hyperemia and blood flow distribution in male and female Fischer 344 rats.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Article
- Pulmonary hypertension impairs vasomotor function in rat diaphragm arterioles.Microvascular research · 2024Article
- The predictive value of neurally adjusted ventilatory assist indexes for the prognosis of patients with severe cerebral hemorrhage.European journal of medical research · 2024Article
- AnFrontiers in bioengineering and biotechnology · 2024Article
- Intraoperative Hemi-Diaphragm Electrical Stimulation Demonstrates Attenuated Mitochondrial Function without Change in Oxidative Stress in Cardiothoracic Surgery Patients.Antioxidants (Basel, Switzerland) · 2023Article
- Pulmonary hypertension alters blood flow distribution and impairs the hyperemic response in the rat diaphragm.Frontiers in physiology · 2023Article
- Reply to Horn et al.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Supplemental oxygen administration during mechanical ventilation reduces diaphragm blood flow and oxygen delivery.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Prolonged Mechanical Ventilation: Outcomes and Management.Journal of clinical medicine · 2022Review
- Reduction in Ventilation-Induced Diaphragmatic Mitochondrial Injury through Hypoxia-Inducible Factor 1α in a Murine Endotoxemia Model.International journal of molecular sciences · 2022Article
- Suppression of Hypoxia-Inducible Factor 1α by Low-Molecular-Weight Heparin Mitigates Ventilation-Induced Diaphragm Dysfunction in a Murine Endotoxemia Model.International journal of molecular sciences · 2021Article
- The role of vascular function on exercise capacity in health and disease.The Journal of physiology · 2021Review
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Mechanical ventilation (MV) is a life-saving intervention, yet with prolonged MV (i.e., ≥6 h) there are time-dependent reductions in diaphragm blood flow and an impaired hyperemic response of unknown origin. Female Sprague-Dawley rats (4-8 mo,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.