Evidence map›Paper›PMID 31161865›Full record

ArticleChannels (Austin, Tex.)2019

Mechano-electrical transduction in trabecular meshwork involves parallel activation of TRPV4 and TREK-1 channels.

Oleg Yarishkin, Jackson M Baumann, David Križaj

Abstract readComment
In one paragraph

Article in Channels (Austin, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Mechanobiology in the eye.npj biological physics and mechanics · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Oleg Yarishkina Department of Ophthalmology and Visual Sciences , University of Utah , Salt lake City , UT , USA.ORCID 0000-0002-8215-7444
Jackson M Baumanna Department of Ophthalmology and Visual Sciences , University of Utah , Salt lake City , UT , USA.
David Križaja Department of Ophthalmology and Visual Sciences , University of Utah , Salt lake City , UT , USA.

Funding

University of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Bryan William Jones · 2005 to 2026
$14.6M
Replacement of the Flexcell Tension systemR01EY027920 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI DAVID KRIZAJ · 2017 to 2026
$3.5M
Vision Research Training Grant at the University of UtahT32EY024234 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI DAVID KRIZAJ, Monica L Vetter · 2014 to 2026
$2.3M
The role of mechanosensation in the vertebrate retinaR01EY022076 · NEI · UNIVERSITY OF UTAH · PI KRIZAJ, DAVID · 2013 to 2017
$1.9M
NEI NIH HHS P30 EY014800NEI NIH HHS R01 EY022076NEI NIH HHS R01 EY027920NEI NIH HHS T32 EY024234
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Potassium Channels, Tandem Pore DomainTRPV Cation ChannelsCalcium SignalingPressureSensitivity and SpecificityTrabecular Meshworkpotassium channel protein TREK-1Potassium Channels, Tandem Pore DomainTRPV Cation ChannelsMechanotransductionTrabecular meshworkTREK-1TRPV4

Identifiers

PMID31161865
PMCPMC6557601

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.