Evidence map›Paper›PMID 31161764›Full record

ArticleJournal of stroke2019

Early Functional Connectivity Predicts Recovery from Visual Field Defects after Stroke.

Yong-Hwan Kim, A-Hyun Cho, Dongho Kim, Seung Min Kim, Hyun Taek Lim, Sun U Kwon, Jong S Kim, Dong-Wha Kang

Open access · diamondAbstract read
In one paragraph

Article in Journal of stroke, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Yong-Hwan KimAsan Institute for Life Sciences, Asan Medical Center, Seoul, Korea.
A-Hyun ChoDepartment of Neurology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Dongho KimAsan Institute for Life Sciences, Asan Medical Center, Seoul, Korea.
Seung Min KimDepartment of Neurology, Veterans Health Service Medical Center, Seoul, Korea.
Hyun Taek LimDepartment of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Sun U KwonDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Jong S KimDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Dong-Wha KangAsan Institute for Life Sciences, Asan Medical Center, Seoul, Korea.
Asan Medical Center · KRUlsan College · KRSeoul Veterans Hospital · KRUniversity of Ulsan · KRYeouido St. Mary's Hospital · KR

Funding

Ministry of Health and Welfare HI12C1847Ministry of Health and Welfare HI18C2383National Research Foundation of Korea 2014R1A2A1A11051280National Research Foundation of Korea 2016R1C1B2015901National Research Foundation of Korea 2017R1A6A3A01001795
6 · The paper itself

Abstract

background and purposeWe aimed to assess whether early resting-state functional connectivity (RSFC) changes measured via functional magnetic resonance imaging (fMRI) could predict recovery from visual field defect (VFD) in acute stroke patients.

methodsPatients with VFD due to acute ischemic stroke in the visual cortex and age-matched healthy controls were prospectively enrolled. Serial resting-state (RS)-fMRI and Humphrey visual field (VF) tests were performed within 1 week and at 1 and 3 months (additional VF test at 6 months) after stroke onset in the patient group. The control group also underwent RS-fMRI and a Humphrey VF test. The changes in RSFCs and VF scores (VFSs) over time and their correlations were investigated.

resultsIn 32 patients (65±10 years, 25 men), the VFSs were lower and the interhemispheric RSFC in the visual cortices was decreased compared to the control group (n=15, 62±6 years, seven men). The VFSs and interhemispheric RSFC in the visual cortex increased mainly within the first month after stroke onset. The interhemispheric RSFC and VFSs were positively correlated at 1 month after stroke onset. Moreover, the interhemispheric RSFCs in the visual cortex within 1 week were positively correlated with the follow-up VFSs.

conclusionsInterhemispheric RSFCs in the visual cortices within 1 week after stroke onset may be a useful biomarker to predict long-term VFD recovery.

Indexed as

Infarction, posterior cerebral arteryMagnetic resonance imagingRecovery of functionVisual fields

Identifiers

PMID31161764
PMCPMC6549059
OpenAlexW2948171533

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.