Evidence map›Paper›PMID 31161714›Full record

ArticlePlant biotechnology journal2020

Overexpression of FBR41 enhances resistance to sphinganine analog mycotoxin-induced cell death and Alternaria stem canker in tomato.

Zhiyong Shao, Yanting Zhao, Lihong Liu, Shanshan Chen, Chuanyou Li, Fanliang Meng, Haoran Liu, Songshen Hu, Jiansheng Wang, Qiaomei Wang

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant biotechnology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
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  4. Recent Advances inJournal of fungi (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zhiyong ShaoState Agricultural Ministry Laboratory of Horticultural Crop Growth and Development, Department of Horticulture, Zhejiang University, Hangzhou, China.
Yanting ZhaoInstitute of Vegetables, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.
Lihong LiuState Agricultural Ministry Laboratory of Horticultural Crop Growth and Development, Department of Horticulture, Zhejiang University, Hangzhou, China.
Shanshan ChenState Agricultural Ministry Laboratory of Horticultural Crop Growth and Development, Department of Horticulture, Zhejiang University, Hangzhou, China.
Chuanyou LiState Key Laboratory of Plant Genomics, National Centre for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Fanliang MengState Agricultural Ministry Laboratory of Horticultural Crop Growth and Development, Department of Horticulture, Zhejiang University, Hangzhou, China.
Haoran LiuState Agricultural Ministry Laboratory of Horticultural Crop Growth and Development, Department of Horticulture, Zhejiang University, Hangzhou, China.
Songshen HuState Agricultural Ministry Laboratory of Horticultural Crop Growth and Development, Department of Horticulture, Zhejiang University, Hangzhou, China.
Jiansheng WangInstitute of Vegetables, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.
Qiaomei WangState Agricultural Ministry Laboratory of Horticultural Crop Growth and Development, Department of Horticulture, Zhejiang University, Hangzhou, China.ORCID 0000-0002-0757-5208
ZheJiang Academy of Agricultural Sciences · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fumonisin B1 (FB1) and Alternaria alternate f. sp. lycopersici (AAL)-toxin are classified as sphinganine analog mycotoxins (SAMTs), which induce programmed cell death (PCD) in plants and pose health threat to humans who consume the contaminated crop products. Herein, Fumonisin B1 Resistant41 (FBR41), a dominant mutant allele, was identified by map-based cloning of Arabidopsis FB1-resistant mutant fbr41, then ectopically expressed in AAL-toxin sensitive tomato (Solanum lycopersicum) cultivar. FBR41-overexpressing tomato plants exhibited less severe cell death phenotype upon AAL-toxin treatment. Analysis of free sphingoid bases showed that both fbr41 and FBR41-overexpressing tomato plants accumulated less sphinganine and phytosphingosine upon FB1 and AAL-toxin treatment, respectively. Alternaria stem canker is a disease caused by AAL and responsible for severe economic losses in tomato production, and FBR41-overexpressing tomato plants exhibited enhanced resistance to AAL with decreased fungal biomass and less cell death, which was accompanied by attenuated accumulation of free sphingoid bases and jasmonate (JA). Taken together, our results indicate that FBR41 is potential in inhibiting SAMT-induced PCD and controlling Alternaria stem canker in tomato.

Indexed as

Genes, PlantMycotoxinsSolanum lycopersicumAlternariaCell DeathDisease ResistanceFumonisinsPlant Diseasesfumonisin B1FumonisinsMycotoxinsAAL-toxinAlternaria alternata f. sp. lycopersiciFumonisin B1 Resistant41programmed cell deathsphinganine analog mycotoxintomato

Identifiers

PMID31161714
PMCPMC6920163
OpenAlexW2948499647

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.