Evidence map›Paper›PMID 31161706›Full record

ArticleAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2019

Underdosing of Benzodiazepines in Patients With Status Epilepticus Enrolled in Established Status Epilepticus Treatment Trial.

Abhishek G Sathe, Holly Tillman, Lisa D Coles, Jordan J Elm, Robert Silbergleit, James Chamberlain, Jaideep Kapur, Hannah R Cock, Nathan B Fountain, Shlomo Shinnar and 4 more

Abstract readLetterComment
In one paragraph

Article in Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Treatment considerations for the management of neonatal onset seizures.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Strategies to innovate emergency care of status epilepticus.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Seizure Management in the Intensive Care Unit.Current treatment options in neurology · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Abhishek G SatheDepartment of Experimental and Clinical Pharmacology, College of Pharmacy and Center for Orphan Drug Research, University of Minnesota, Minneapolis, MN.ORCID 0000-0002-7348-4208
Holly TillmanDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC.
Lisa D ColesDepartment of Experimental and Clinical Pharmacology, College of Pharmacy and Center for Orphan Drug Research, University of Minnesota, Minneapolis, MN.
Jordan J ElmDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, SC.
Robert SilbergleitDepartment of Emergency Medicine, University of Michigan, Ann Arbor, MI.
James ChamberlainDivision of Emergency Medicine, Children's National Health System, and the Department of Pediatrics and Emergency Medicine, School of Medicine and Health Sciences, George Washington University Washington, DC.
Jaideep KapurDepartment of Neurology, University of Virginia, Charlottesville, VA.
Hannah R CockSt. George's University of London and St. George's University Hospitals NHS Foundation Trust, London, UK.
Nathan B FountainDepartment of Neurology, University of Virginia, Charlottesville, VA.
Shlomo ShinnarMontefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.
Daniel H LowensteinDepartment of Neurology, University of California, San Francisco, CA.
Robin A ConwitNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
Thomas P BleckFeinberg School of Medicine, Northwestern University and Rush Medical College, Chicago, IL.
James C CloydDepartment of Experimental and Clinical Pharmacology, College of Pharmacy and Center for Orphan Drug Research, University of Minnesota, Minneapolis, MN.

Funding

Neurologic Emergencies Treatment Trials Network: Clinical Coordinating CenterU01NS056975 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BARSAN, WILLIAM G · 2006 to 2015
$40.4M
Established Status Epilepticus Treatment Trial (ESETT)U01NS088034 · NINDS · UNIVERSITY OF VIRGINIA · PI CHAMBERLAIN, JAMES, KAPUR, JAIDEEP · 2014 to 2018
$16.3M
Neurological Emergencies Treatment Trials Network Statistical and Data ManagementU01NS059041 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DURKALSKI, VALERIE L, PALESCH, YUKO Y · 2006 to 2015
$9.1M
Established Status Epilepticus Treatment Trial (ESETT) - SDMCU01NS088023 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ELM, JORDAN J. · 2014 to 2018
$2.0M
ESETT Pharmacokinetic-Pharmacodynamic StudyR01NS099653 · NINDS · UNIVERSITY OF MINNESOTA · PI CLOYD, JAMES C., COLES, LISA D · 2017 to 2019
$1.0M
NINDS NIH HHS R01 NS099653NINDS NIH HHS U01 NS056975NINDS NIH HHS U01 NS059041NINDS NIH HHS U01 NS088023NINDS NIH HHS U01 NS088034
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BenzodiazepinesStatus EpilepticusHumansBenzodiazepines

Identifiers

PMID31161706
PMCPMC8366410

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.