Evidence map›Paper›PMID 31161658›Full record

Observational studyJournal of diabetes investigation2020

Evaluation of effectiveness of treatment paradigm for newly diagnosed type 2 diabetes patients in Chin: A nationwide prospective cohort study.

Xiaoling Cai, Dayi Hu, Changyu Pan, Guangwei Li, Juming Lu, Qiuhe Ji, Benli Su, Haoming Tian, Shen Qu, Jianping Weng and 3 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of diabetes investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. A Guideline-Based Decision Tree Achieves Better Glucose Control with Less Hypoglycemia at 3 Months in Chinese Diabetic Patients.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021
    Article
  6. Article
  7. Review
  8. Article
  9. Observational
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiaoling CaiDepartments of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, China.
Dayi HuCardiology, Peking University People's Hospital, Beijing, China.
Changyu PanDepartment of Endocrinology and Metabolism, Chinese People's Liberation Army General Hospital, Beijing, China.
Guangwei LiDepartment of Endocrinology and Metabolism, Fuwai Hospital, Beijing, China.
Juming LuDepartment of Endocrinology and Metabolism, Chinese People's Liberation Army General Hospital, Beijing, China.
Qiuhe JiDepartment of Endocrinology and Metabolism, The Fourth Military Medical University Xi Jing Hospital, Xi An, China.ORCID https://orcid.org/0000-0002-3010-5837
Benli SuDepartment of Endocrinology and Metabolism, The Second Affiliated Hospital Dalian Medical University, Dalian, China.
Haoming TianDepartment of Endocrinology and Metabolism, Sichuan University West China Hospital, Chengdu, China.
Shen QuDepartment of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Shanghai, China.
Jianping WengDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Danyi ZhangVitalStrategic Research Institute, Shanghai, China.
Jie XuVitalStrategic Research Institute, Shanghai, China.
Linong JiDepartments of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, China.

Funding

Bristol-Myers Squibb (China) company
6 · The paper itself

Abstract

AIMS/

introductionData of nationwide glycemic control and hypoglycemic treatment patterns in newly diagnosed type 2 diabetes patients in China are absent. The aim of this study was to assess the evolution of treatment patterns for newly diagnosed type 2 diabetes patients and the clinical outcomes during 12-month follow up. MATERIALS AND

methodsThis is an observational prospective cohort study with 12 months of follow up. Patients with a diagnosis of type 2 diabetes for <6 months were enrolled. Glycated hemoglobin A1c (HbA1c) levels and hypoglycemic treatment patterns were collected at baseline and at every 3 months of follow up.

resultsA total of 79 hospitals were recruited, consisting of 5,770 participants. The mean HbA1c was 8.4 ± 2.5% at baseline, and decreased to 6.7 ± 1.2% at 12 months with 68.5% of patients achieving HbA1c <7%. At baseline, 44.6% of the patients were without hypoglycemic medications, 37.7% had oral hypoglycemic agents and 17.7% received insulin treatment. Determinants of change in HbA1c were treatment patterns, comorbidities, baseline characteristics such as obesity and smoking, regions, and tiers of hospitals. Associated factors with treatment alterations were time of follow up, treatment patterns, patient-reported reasons such as the economic factors and poor efficacy.

conclusionsIn newly diagnosed type 2 diabetes patients, compared with patients without medications, patients with one oral hypoglycemic agent had higher possibilities of reaching glycemic control, whereas patients using insulin had lower possibilities of reaching the target. Factors associated with change in HbA1c and treatment alterations were also revealed.

Indexed as

BiomarkersBlood GlucoseChinaDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGlycated HemoglobinHumansHypoglycemiaHypoglycemic AgentsMaleMiddle AgedPrognosisProspective StudiesBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsClinical effectivenessNewly diagnosedType 2 diabetes

Identifiers

PMID31161658
PMCPMC6944848

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.