Evidence map›Paper›PMID 31161579›Full record

ReviewCurrent nutrition reports2019

Targeting Carbohydrates and Polyphenols for a Healthy Microbiome and Healthy Weight.

Matthias Van Hul, Patrice D Cani

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Current nutrition reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04611217 (Mechanisms Linking Dietary Fiber, the Microbiome and Satiety), which is not on this map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04611217 narecruitingnot on this mapstarted 2021, after this paper: background citation

Mechanisms Linking Dietary Fiber, the Microbiome and Satiety

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2021 to 2025Enrolled88ConditionsDietary FiberArmsDietary fiber: 10-25g, Dietary fiber: 5g
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Biological Mechanisms of Polyphenols againstInfectious disorders drug targets · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Gut Microbiota Modulation by Bioactive Compounds from Ilex paraguariensis: an In Vivo Study.Plant foods for human nutrition (Dordrecht, Netherlands) · 2023
    Article
  14. Life (Basel, Switzerland) · 2023
    Article
  15. Review
  16. Article
  17. Article
  18. Mangrove fruit (Heliyon · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthias Van HulUniversité catholique de Louvain, WELBIO- Walloon Excellence in Life Sciences and BIOtechnology, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, UCLouvain, Av. E. Mounier, 73 box B1.73.11, B-1200, Brussels, Belgium.
Patrice D CaniUniversité catholique de Louvain, WELBIO- Walloon Excellence in Life Sciences and BIOtechnology, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, UCLouvain, Av. E. Mounier, 73 box B1.73.11, B-1200, Brussels, Belgium. patrice.cani@uclouvain.be.
Walloon Excellence in Lifesciences and Biotechnology · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewIn this review, we focus on microbiota modulation using non-digestible carbohydrate and polyphenols (i.e., prebiotics) that have the potential to modulate body weight. RECENT

findingsPrebiotics derived from plants have gained the interest of public and scientific communities as they may prevent diseases and help maintain health. Maintaining a healthy body weight is key to reducing the risk of developing chronic metabolic complications. However, the prevalence of obesity has increased to pandemic proportions and is now ranked globally in the top five risk factors for death. While diet and behavioral modification programs aiming to reduce weight gain and promote weight loss are effective in the short term, they remain insufficient over the long haul as compliance is often low and weight regain is very common. As a result, novel dietary strategies targeting the gut microbiota have been successful in decreasing obesity and metabolic disorders via different molecular mechanisms.

Indexed as

Body WeightCarbohydrate MetabolismDietDietary CarbohydratesDietary FiberGastrointestinal MicrobiomeGastrointestinal TractMetabolic DiseasesObesityPolyphenolsPrebioticsProbioticsRisk FactorsWeight LossDietary CarbohydratesDietary FiberPolyphenolsPrebioticsDietary fibersGut microbiotaObesityPolyphenolsPrebiotics

Identifiers

PMID31161579
PMCPMC6904403
OpenAlexW2948928801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.