Evidence map›Paper›PMID 31161476›Full record

ArticleCellular and molecular neurobiology2019

High-Fat Diets and LXRs Expression in Rat Liver and Hypothalamus.

Mariana Rey, María Sol Kruse, Rocío Nahimé Magrini-Huamán, Héctor Coirini

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Antioxidants (Basel, Switzerland) · 2024
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  7. Metabolites · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mariana ReyLaboratorio de Neurobiologia, Instituto de Biologia y Medicina Experimental (IBYME-CONICET), Vuelta de Obligado 2490, C1428ADN, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina.
María Sol KruseLaboratorio de Neurobiologia, Instituto de Biologia y Medicina Experimental (IBYME-CONICET), Vuelta de Obligado 2490, C1428ADN, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina.
Rocío Nahimé Magrini-HuamánLaboratorio de Neurobiologia, Instituto de Biologia y Medicina Experimental (IBYME-CONICET), Vuelta de Obligado 2490, C1428ADN, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina.
Héctor CoiriniLaboratorio de Neurobiologia, Instituto de Biologia y Medicina Experimental (IBYME-CONICET), Vuelta de Obligado 2490, C1428ADN, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina. hcoirini@ibyme.conicet.gov.ar.
Experimental Medicine and Biology Institute · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad Católica de Cuyo · AR

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas PIP-0243Consejo Nacional de Investigaciones Científicas y Técnicas PIP-860
6 · The paper itself

Abstract

Disturbances on lipid metabolism are associated with health disorders. High-fat diets (HFDs) consumption promotes cardiovascular and neurodegenerative diseases where cholesterol plays an important role. Among regulators of this steroid homeostasis, the liver X receptors (LXRs) induce genes that protect cells from cholesterol overload. We previously described how both hypothalamic LXRα and LXRβ are sensitive to a high-fructose diet, suggesting that these receptors trigger responses related to control of energy and food intake. The present work's main objective was to study the effect of different HFDs on LXRs expression (in hypothalamus and liver), and lipid profile. Male rats received control diet (CD), HFD

Indexed as

Diet, High-FatAnimalsHypothalamusLipid MetabolismLiverLiver X ReceptorsMaleRats, Sprague-DawleyLiver X ReceptorsCholesterolCholic acidHigh-fat dietsOxysterolsTriglycerides

Identifiers

PMID31161476
PMCPMC11457829
OpenAlexW2948158017

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.