Evidence map›Paper›PMID 31161459›Full record

ArticleEJNMMI research2019

Comparison of the radiolabeled PSMA-inhibitor

Romain Schollhammer, Henri De Clermont Gallerande, Mokrane Yacoub, Marie-Laure Quintyn Ranty, Nicole Barthe, Delphine Vimont, Elif Hindié, Philippe Fernandez, Clément Morgat

Open access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Dual-tracer PET/CT with [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  2. Comparison ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Trial
  3. Value ofEuropean radiology · 2023
    Trial
  4. Prospective head-to-head comparison of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Design and Synthesis ofChemMedChem · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. A prospective comparative study of [European journal of nuclear medicine and molecular imaging · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. [Molecules (Basel, Switzerland) · 2022
    Article
  15. Review
  16. Pharmaceutics · 2021
    Article
  17. Review
  18. Effect of the versatile bifunctional chelator AAZTAEJNMMI radiopharmacy and chemistry · 2020
    Article
  19. Radiation doses fromEJNMMI physics · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Romain SchollhammerNuclear Medicine Department, University Hospital of Bordeaux, Place Amélie Raba Léon, 33000, 33076, Bordeaux, France. romain.scho@gmail.com.
Henri De Clermont GallerandeNuclear Medicine Department, University Hospital of Bordeaux, Place Amélie Raba Léon, 33000, 33076, Bordeaux, France.
Mokrane YacoubDepartment of Pathology, University Hospital of Bordeaux, 33076, Bordeaux, France.
Marie-Laure Quintyn RantyDepartment of Pathology, University Hospital of Toulouse, 31000, Toulouse, France.
Nicole BartheBioTis, Inserm U1026, Bordeaux, France.
Delphine VimontUniversity of Bordeaux, INCIA, UMR5287, 33400, Talence, France.
Elif HindiéNuclear Medicine Department, University Hospital of Bordeaux, Place Amélie Raba Léon, 33000, 33076, Bordeaux, France.
Philippe FernandezNuclear Medicine Department, University Hospital of Bordeaux, Place Amélie Raba Léon, 33000, 33076, Bordeaux, France.
Clément MorgatNuclear Medicine Department, University Hospital of Bordeaux, Place Amélie Raba Léon, 33000, 33076, Bordeaux, France.
Centre National de la Recherche Scientifique · FRInserm · FRUniversité de Bordeaux · FRUniversité Fédérale de Toulouse Midi-Pyrénées · FR

Funding

La ligue contre le Cancer de Gironde 2016
6 · The paper itself

Abstract

purposeProstate-specific membrane antigen (PSMA) and gastrin-releasing peptide receptor (GRP-R) are expressed in prostate cancer and can be targeted with radiolabeled inhibitors and antagonists. Their performances for the initial characterization of prostatic tumors have been barely evaluated but never compared. We aimed to gather comparative preclinical data of the role of PSMA and GRP-R targeting in prostate cancer. PROCEDURES: We retrospectively studied 20 frozen prostatectomy samples with various metastatic risks of the D'Amico classification. Tissue samples were investigated by tissular microimaging using the radiolabeled PSMA inhibitor

resultsBinding of

conclusionPSMA and GRP-R based imaging might have complementary performances for the initial characterization of prostatic tumors. Prospective clinical studies comparing the two tracers in this setting are needed.

Indexed as

GRP-RProstate cancerPSMA

Identifiers

PMID31161459
PMCPMC6546761
OpenAlexW2948239425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.