Evidence map›Paper›PMID 31161374›Full record

ArticleJournal of cancer research and clinical oncology2019

Safety and efficacy of

Zhanwang Xiang, Mingjun Bai, Guohong Li, Bihui Zou, Zhihui Zhong, Fei Gao, Chun Wu, Mingsheng Huang, Fujun Zhang

Open access · greenAbstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. The Clinical Value of Computed Tomography (CT)-GuidedCancer management and research · 2021
    Article
  4. Review
  5. Evaluation of radioactiveBMC cancer · 2020
    Article
  6. OncoTargets and therapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhanwang XiangDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, 510630, China.
Mingjun BaiDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, 510630, China.
Guohong LiDepartment of Radiology, Guangdong Second Provincial General Hospital, Guangdong Provincial Emergency Hospital, 466 Xingang Road, Middle, Guangzhou, 510000, China.
Bihui ZouSun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road, East, Guangzhou, 510060, China.
Zhihui ZhongSun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road, East, Guangzhou, 510060, China.
Fei GaoSun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road, East, Guangzhou, 510060, China.
Chun WuDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, 510630, China.
Mingsheng HuangDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-sen University, 600 Tianhe Road, Guangzhou, 510630, China. huangmsh@mail.sysu.edu.com.
Fujun ZhangSun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road, East, Guangzhou, 510060, China. zhangfj@sysucc.org.cn.ORCID http://orcid.org/0000-0002-7978-5992
Sun Yat-sen University · CNGuangdong Provincial People's Hospital · CN

Funding

National Natural Science Foundation of China 81371654National Natural Science Foundation of China 81571780Natural Science Foundation of Guangdong Province 2018A0303130050
6 · The paper itself

Abstract

purposeTo evaluate the safety and efficacy of MATERIALS AND

methodsWe retrospectively recruited 95 patients with bilateral lung recurrences from hepatocellular carcinoma (HCC) after resection or ablation who had received 3-6-month sorafenib with or without stereotactic body radiotherapy (SBRT), from October 2011 to January 2015; patients were then randomly divided into two groups, 44 patients received computed tomography (CT)-guided

resultsThe median survival time was 19 months (range of 3-36 months). The local response rate (LRR) at 3, 6, 12, 18, 24, 30 and 36 months in group A was 81.8%, 65.9%, 59.1%, 45.0%, 38.6%, 22.7%, 11.4%, respectively, and 64.7%, 47.1%, 33.3%, 25.4%, 15.7%, 11.7%, 7.8%, respectively, in group B (P < 0.05). The mean progression-free survival time (PFST) and overall survival (OS) of group A were significantly longer than those of group B. Alpha fetoprotein (AFP) and tumor size were independent factors that affected the PFST and OS, normal AFP levels and less than 1-cm tumor diameter had better PFST and OS (P < 0.05). No massive bleeding or serious complications occurred.

conclusionCT-guided

Indexed as

BrachytherapyCarcinoma, HepatocellularFemaleHumansIodine RadioisotopesLiver NeoplasmsMaleMiddle AgedRetrospective StudiesIodine-125Iodine Radioisotopes125I brachytherapyBilateral lung recurrencesEfficacyHepatocellular carcinomaSafety

Identifiers

PMID31161374
PMCPMC11810356
OpenAlexW2948994561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.