ArticleEuropean radiology2019
Differentiating between malignant and benign renal tumors: do IVIM and diffusion kurtosis imaging perform better than DWI?
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed.
- Head-to-head comparison of quantitative perfusion parameters derived from DECT, IVIM, and DCE-MRI for renal mass characterization: a within-patient, prospective study.Abdominal radiology (New York) · 2026Article
- Estimating the Sodium Content: A Case Series of Benign and Malignant Renal Tumours UsingNMR in biomedicine · 2026Article
- Assessment of renal interstitial fibrosis in glomerulonephritis using compartmental and non-compartmental diffusion magnetic resonance imaging.La Radiologia medica · 2026Article
- Lymphoma classification with multi-parametric texture analysis of DWI and PET imaging in Hodgkin and non-Hodgkin lymphoma: a pilot study.Magma (New York, N.Y.) · 2026Article
- Multiparametric diffusion-weighted MRI for renal microstructural assessment in patients with primary aldosteronism at varying direct renin concentrations.Abdominal radiology (New York) · 2026Article
- Multiparametric magnetic resonance imaging in differentiating benign and malignant sinonasal masses: A prospective study and literature review.World journal of methodology · 2026Article
- Dual deep learning approach for non-invasive renal tumour subtyping with VERDICT-MRI.Npj imaging · 2026Article
- Commentary: Grading of clear cell renal cell carcinoma using diffusion MRI with a multimodal apparent diffusion model.Frontiers in oncology · 2026Article
- Evaluation of Renal Perfusion: A Comparative Study between Intravoxel Incoherent Motion (IVIM) Imaging and Arterial Spin Labeling (ASL) to Assess Renal Blood Flow in Rodents.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Evaluation of Early Renal Changes in Type 2 Diabetes Mellitus Using Multiparametric MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Diffusion kurtosis versus diffusion-weighted magnetic resonance imaging in differentiating clear cell renal cell carcinoma and renal angiomyolipoma with minimal fat: a comparative study.Diagnostic and interventional radiology (Ankara, Turkey) · 2025Article
- Diagnosing placenta accreta spectrum in different placental locations using a combination of magnetic resonance imaging (MRI) features and diffusion-weighted MRI parameters.Quantitative imaging in medicine and surgery · 2025Article
- Deep learning-based prediction of tumor aggressiveness in RCC using multiparametric MRI: a pilot study.International urology and nephrology · 2025Article
- Quantitative diffusion MRI biomarkers predict adverse maternal outcomes in placenta accreta spectrum disorders.Frontiers in medicine · 2025Article
- CECT-Based Radiomic Nomogram of Different Machine Learning Models for Differentiating Malignant and Benign Solid-Containing Renal Masses.Journal of multidisciplinary healthcare · 2025Article
- Exploring the value of arterial spin labeling and six diffusion MRI models in differentiating solid benign and malignant renal tumors.European radiology experimental · 2024Article
- Feasibility and Reproducibility of T2 Mapping Compared with Diffusion-Weighted Imaging in Solid Renal Masses.Bioengineering (Basel, Switzerland) · 2024Article
- Intravoxel incoherent motion diffusion-weighted imaging in evaluating preoperative staging of esophageal squamous cell carcinoma : Evaluation of preoperative stage of primary tumour and prediction of lymph node metastases from esophageal cancer using IVIM: a prospective study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- High-resolution and highly accelerated MRI T2 mapping as a tool to characterise renal tumour subtypes and grades.European radiology experimental · 2024Article
- Comparison of conventional diffusion-weighted imaging and intravoxel incoherent motion in differentiating between chromophobe renal cell carcinoma and renal oncocytoma: a preliminary study.The British journal of radiology · 2024Article
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8 authors.
Funding
Abstract
objectiveTo quantitatively compare the diagnostic values of conventional diffusion-weighted imaging (DWI), intravoxel incoherent motion (IVIM), and diffusion kurtosis imaging (DKI) in differentiating between malignant and benign renal tumors.
methodsMultiple b value DWIs and DKIs were performed in 180 patients with renal tumors, which were divided into clear cell renal cell carcinoma (ccRCC), non-ccRCC, and benign renal tumor group. The apparent diffusion coefficient (ADC), true diffusivity (D), pseudo-diffusion coefficient (D*), perfusion fraction (f), mean kurtosis (MK), and mean diffusivity (MD) maps were calculated. The diagnostic efficacy of various diffusion parameters for predicting malignant renal tumors was compared.
resultsThe ADC, D, and MD values of ccRCCs were higher, while D*, f, and MK values were lower than those of benign renal tumors (all p < 0.025). The D* and f values of non-ccRCCs were lower than those of benign renal tumors (p = 0.002 and p < 0.001, respectively). The difference of ADC, D, MD, and MK values between non-ccRCCs and benign renal tumors was not statistically significant (p > 0.05). The ADC, D, MD, and f values of ccRCCs were higher, while MK values were lower than those of non-ccRCCs (all p < 0.001). The AUC values of ADC, D, D*, f, MK, and MD were 0.849, 0.891, 0.708, 0.656, 0.862, and 0.838 for differentiating ccRCCs from benign renal tumors, respectively. The AUC values of D* and f were 0.772 and 0.866 for discrimination between non-ccRCCs and benign renal tumors, respectively.
conclusionIVIM parameters are the best, while DWI and DKI parameters have similar performance in differentiating malignant and benign renal tumors. KEY POINTS: • The D value is the best parameter for differentiating ccRCC from benign renal tumors. • The f value is the best parameter for differentiating non-ccRCC from benign renal tumors. • Conventional DWI and DKI have similar performance in differentiating malignant and benign renal tumors.
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