ArticleJournal of laboratory physicians
Subclinical inflammation markers in hyperemesis gravidarum and ketonuria: A case-control study.
Article in Journal of laboratory physicians. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Laboratory and Clinical Values of the Neutrophil-to-Lymphocyte Ratio in Women With Hyperemesis Gravidarum: A Systematic Review and Meta-Analysis.Journal of pregnancy · 2025Pooled it
- Article
- Prevalence of hyperemesis gravidarum and its associated electrolyte and hematologic disturbances in pregnant women.Frontiers in medicine · 2026Article
- Inflammation-driven pathogenesis of hyperemesis gravidarum: assessing the role of pan-immune-inflammation value and hematologic parameters.Archives of gynecology and obstetrics · 2025Article
- Determination of the relationships between hyperemesis gravidarum and systemic inflammation markers: a case‒control study.BMC pregnancy and childbirth · 2025Article
- Relationship of hyperemesis gravidarum with platelet crit, hemoglobin-to-red cell distribution width ratio, and neutrophil-to-lymphocyte ratio.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Blood-Based Clinical Biomarkers of Inflammation and Nutrition in Hyperemesis Gravidarum.Journal of clinical medicine · 2024Article
- Predictability of Hematological Parameters in the Diagnosis of Cesarean Scar Pregnancy.Journal of laboratory physicians · 2023Article
- Hematological Parameters to Predict the Severity of Hyperemesis Gravidarum and Ketonuria.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022Article
- The Red Blood Cell Distribution Width-Albumin Ratio Was a Potential Prognostic Biomarker for Diabetic Ketoacidosis.International journal of general medicine · 2021Article
- Development and Validation of a Risk Prediction Model for In-Hospital Mortality in Patients With Acute Upper Gastrointestinal Bleeding.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionSubclinical inflammation markers play a significant role in hyperemesis gravidarum (HEG). Simple hematological markers such as mean platelet volume (MPV), platelet distribution width (PDW), neutrophil-to-lymphocyte ratio (NLR), red cell distribution width (RDW), plateletcrit (PCT), and platelet-to-lymphocyte ratio (PLR) have been shown to reflect inflammatory burden and disease activity in several disorders. Ketonuria is a parameter used in the diagnosis of severe HEG, but its correlation with disease severity remains controversial. The relationship of subclinical inflammation markers with degree of ketonuria has not been examined previously. In this study, we aimed to determine the diagnostic value of these subclinical inflammation markers and the relationship between these markers and grade of ketonuria in patients with HEG. MATERIALS AND
methodsA total of 94 pregnant women with a diagnosis of HEG and 100 gestational age-matched healthy pregnant women were enrolled in this retrospective study. MPV, PDW, NLR, PLR, PCT, and ketonuria were calculated and analyzed from complete blood cell counts and total urine analyses.
resultsLymphocyte count was significantly higher in the control group (
conclusionsPLR and NLR can be considered effective markers to aid in the diagnosis of HEG. No marker was found to correlate with ketonuria grade except RDW, although the relationship of the severity of ketonuria with severity of disease is controversial. RDW increases as the degree of ketonuria increases.
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