Evidence map›Paper›PMID 31160758›Full record

ArticleCellular & molecular immunology2019

The selective retinoic acid receptor-α agonist AM580 fails to control autoimmune neuroinflammation.

Qing Wang, Rodolfo Thome, Abdolmohamad Rostami, Cun-Gen Ma, Guang-Xian Zhang

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular & molecular immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qing WangDepartment of Neurology, Thomas Jefferson University, 900 Walnut Street, Suite 300, Philadelphia, PA, 19107, USA.
Rodolfo ThomeDepartment of Neurology, Thomas Jefferson University, 900 Walnut Street, Suite 300, Philadelphia, PA, 19107, USA.
Abdolmohamad RostamiDepartment of Neurology, Thomas Jefferson University, 900 Walnut Street, Suite 300, Philadelphia, PA, 19107, USA.
Cun-Gen MaThe Key Research Laboratory for the Study of Beneficial Qi and the Blood Circulation Activation Method in Treating Multiple Sclerosis, State Administration of Traditional Chinese Medicine, Research Center of Neurobiology, Shanxi University of Chinese Medicine, Taiyuan, 030024, China. macungen2001@163.com.
Guang-Xian ZhangDepartment of Neurology, Thomas Jefferson University, 900 Walnut Street, Suite 300, Philadelphia, PA, 19107, USA. guang-xian.zhang@jefferson.edu.

Funding

Ursolic acid: a novel oral therapy for chronic stage of MS/EAE by both immunomodulation and neural repairR01NS099594 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI ZHANG, GUANG-XIAN · 2017 to 2021
$1.7M
P7C3 as a novel immunomodulator for CNS autoimmunityR21AI135601 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI ZHANG, GUANG-XIAN · 2018 to 2019
$429k
NIAID NIH HHS R21 AI135601NINDS NIH HHS R01 NS099594
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Inflammatory AgentsBenzoatesDisease Models, AnimalEncephalomyelitis, Autoimmune, ExperimentalMiceMice, Inbred C57BLNeuroprotective AgentsRetinoic Acid Receptor alphaTetrahydronaphthalenesTreatment FailureAm 580Anti-Inflammatory AgentsBenzoatesNeuroprotective AgentsRara protein, mouseRetinoic Acid Receptor alphaTetrahydronaphthalenes

Identifiers

PMID31160758
PMCPMC6804666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.