Evidence map›Paper›PMID 31160748›Full record

ArticleScientific reports2019

Genetic variability of porcine pegivirus in pigs from Europe and China and insights into tissue tropism.

Johanna Kennedy, Vanessa Maria Pfankuche, Doris Hoeltig, Alexander Postel, Oliver Keuling, Malgorzata Ciurkiewicz, Wolfgang Baumgärtner, Paul Becher, Christine Baechlein

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Johanna KennedyInstitute of Virology, University of Veterinary Medicine Hannover, 30559, Hannover, Germany.
Vanessa Maria PfankucheDepartment of Pathology, University of Veterinary Medicine Hannover, 30559, Hannover, Germany.
Doris HoeltigClinic for Swine, Small Ruminants, Forensic Medicine and Ambulatory Services, University of Veterinary Medicine Hannover, 30173, Hannover, Germany.
Alexander PostelInstitute of Virology, University of Veterinary Medicine Hannover, 30559, Hannover, Germany.ORCID http://orcid.org/0000-0002-1187-1069
Oliver KeulingInstitute for Terrestrial and Aquatic Wildlife Research, University of Veterinary Medicine Hannover, 30173, Hannover, Germany.ORCID http://orcid.org/0000-0002-9052-6860
Malgorzata CiurkiewiczDepartment of Pathology, University of Veterinary Medicine Hannover, 30559, Hannover, Germany.ORCID http://orcid.org/0000-0001-6277-7366
Wolfgang BaumgärtnerDepartment of Pathology, University of Veterinary Medicine Hannover, 30559, Hannover, Germany.
Paul BecherInstitute of Virology, University of Veterinary Medicine Hannover, 30559, Hannover, Germany. paul.becher@tiho-hannover.de.ORCID http://orcid.org/0000-0001-7857-1354
Christine BaechleinInstitute of Virology, University of Veterinary Medicine Hannover, 30559, Hannover, Germany. christine.baechlein@tiho-hannover.de.
University of Veterinary Medicine Hannover, Foundation · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pegiviruses belong to the family Flaviviridae and have been found in humans and other mammalian species. To date eleven different pegivirus species (Pegivirus A-K) have been described. However, little is known about the tissue tropism and replication of pegiviruses. In 2016, a so far unknown porcine pegivirus (PPgV, Pegivirus K) was described and persistent infection in the host, similar to human pegivirus, was reported. In this study, qRT-PCR, phylogenetic analyses and fluorescence in situ hybridization (FISH) were implemented to detect and quantify PPgV genome content in serum samples from domestic pigs from Europe and Asia, in tissue and peripheral blood mononuclear cell (PBMC) samples and wild boar serum samples from Germany. PPgV was detectable in 2.7% of investigated domestic pigs from Europe and China (viral genome load 2.4 × 10

Indexed as

AnimalsAsiaChinaEuropeFlaviviridaeFlaviviridae InfectionsGenome, ViralGermanyHumansIn Situ Hybridization, FluorescenceLeukocytes, MononuclearPhylogenyRNA, ViralSus scrofaSwineTropismRNA, Viral

Identifiers

PMID31160748
PMCPMC6547670
OpenAlexW2947506253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.