Evidence map›Paper›PMID 31160474›Full record

SynthesisClinical medicine & research2019

Assessing Prognosis of Acute Coronary Syndrome in Recent Clinical Trials: A Systematic Review.

Fan Ye, David Winchester, Michael Jansen, Arthur Lee, Burton Silverstein, Carolyn Stalvey, Matheen Khuddus, Joseph Mazza, Steven Yale

Abstract readSystematic Review
In one paragraph

Synthesis in Clinical medicine & research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fan YeGraduate Medical Education, University of Central Florida College of Medicine, Orlando, FL USA.
David WinchesterDepartment of Cardiology, University of Florida College of Medicine, Gainesville, FL USA.
Michael JansenThe Cardiac and Vascular Institute, Gainesville, FL USA.
Arthur LeeThe Cardiac and Vascular Institute, Gainesville, FL USA.
Burton SilversteinThe Cardiac and Vascular Institute, Gainesville, FL USA.
Carolyn StalveyDepartment of General Internal Medicine, University of Florida College of Medicine, Gainesville, FL USA.
Matheen KhuddusThe Cardiac and Vascular Institute, Gainesville, FL USA.
Joseph MazzaMarshfield Clinic Research Institute, Marshfield, WI USA.
Steven YaleDepartment of Internal Medicine, University of Central Florida College of Medicine, Orlando, FL USA steven.yale.md@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is no recent comprehensive overview of contemporary clinical trials assessing short and long-term outcomes in patients with acute coronary syndrome (ACS). This paper reviews factors from recent clinical trials that influenced prognosis in patients with ACS. Cochrane and PubMed databases were screened systematically for clinical trials published in the English literature reporting on ACS prognosis. Two authors independently screened titles, abstracts, and full text. Studies meeting inclusion criteria evaluated the impact of modern practice on prognosis. In vitro and animal models studies, conference abstracts, imaging studies, and review articles were excluded. Disagreement in inclusion criteria was resolved by consensus. A large study of 8,859 patients showed no difference in all-cause mortality between 31 days and 2 years in patients with ST segment elevation myocardial infarction (STEMI) compared to those with non-ST segment elevation myocardial infarction (NSTEMI) or stable ischemic heart disease (SIHD). Other studies showed a significant increase in all-cause mortality in patients with STEMI within the first 30 days, with NSTEMI patients exhibiting a higher mortality rate compared to those with SIHD during the 2-year follow-up period. Our review found that women have a poorer short-term prognosis compared to men. Additionally, reports from patients receiving comprehensive and coordinated care showed longer survival rates. In view of the improved prognosis demonstrated for patients suffering from ACS, assessing prognosis in patients represents a formidable task in modern practice. Our review highlights the need for further evidence-based studies evaluating long-term outcomes on diagnostic and treatment strategies.

Indexed as

Acute Coronary SyndromeST Elevation Myocardial InfarctionAgedAnimalsDisease-Free SurvivalDisease Models, AnimalFemaleHumansMaleMiddle AgedSex FactorsSurvival RateTime FactorsAnginaCardiovascular diseaseClinical trialHeart failurePatient outcomesPrognosisReviewSystematic

Identifiers

PMID31160474
PMCPMC6546278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.