Evidence map›Paper›PMID 31160382›Full record

ArticleMolecular cancer research : MCR2019

Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics.

Olesja Popow, João A Paulo, Michael H Tatham, Melanie S Volk, Alejandro Rojas-Fernandez, Nicolas Loyer, Ian P Newton, Jens Januschke, Kevin M Haigis, Inke Näthke

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. YTHDF3 Promoted Gastric Cancer Progression by Facilitating mAnalytical cellular pathology (Amsterdam) · 2026
    Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Olesja PopowCancer Research Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.ORCID 0000-0002-9683-5971
João A PauloDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-4291-413X
Michael H TathamCentre for Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.
Melanie S VolkCell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.ORCID 0000-0002-5198-8376
Alejandro Rojas-FernandezCenter for Interdisciplinary Studies on the Nervous System (CISNe) and Institute of Medicine, Universidad Austral de Chile, Valdivia, Chile.
Nicolas LoyerCell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.
Ian P NewtonCell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.ORCID 0000-0002-5083-0585
Jens JanuschkeCell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom.
Kevin M HaigisCancer Research Institute and Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.ORCID 0000-0003-1922-4509
Inke NäthkeCell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, Scotland, United Kingdom. I.s.nathke@dundee.ac.uk.ORCID 0000-0003-2420-4385
University of Dundee · GBBeth Israel Deaconess Medical Center · USAustral University of Chile · CLHarvard University · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Cale Whitworth · 2014 to 2026
$13.5M
A multi-faceted approach to identifying K-Ras synthetic lethal relationshipsU01CA199252 · NCI · DANA-FARBER CANCER INST · PI ELLEDGE, STEPHEN J, HAIGIS, KEVIN · 2015 to 2019
$4.7M
Advancing Multiplexed Isobaric Tag-based Strategies for Proteome ProfilingR01GM132129 · NIGMS · HARVARD MEDICAL SCHOOL · PI PAULO, JOAO A · 2019 to 2023
$1.7M
Resolving the role of nicotine-mediated phosphorylation on pancreatic fibrosisK01DK098285 · NIDDK · HARVARD MEDICAL SCHOOL · PI PAULO, JOAO A · 2013 to 2017
$638k
Cancer Research UK A11243Cancer Research UK A12975Cancer Research UK A13067Cancer Research UK C434/A13067Cancer Research UK C5314/A12975NCI NIH HHS U01 CA199252NIDDK NIH HHS K01 DK098285NIGMS NIH HHS R01 GM132129NIH HHS P40 OD018537Wellcome Trust 100031Wellcome Trust 101468Wellcome Trust 203962Wellcome Trust WT 203962/Z/16/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenomatous Polyposis Coli ProteinAnimalsAnimals, Genetically Modifiedbeta CateninCell Line, TumorDrosophilaGene Expression Regulation, NeoplasticHCT116 CellsHeLa CellsHumansMiceNeoplasmsProtein Interaction MapsProtein Serine-Threonine KinasesProteomicsTandem Mass SpectrometryAdenomatous Polyposis Coli ProteinAPC protein, humanbeta CateninCTNNB1 protein, humanMINK1 protein, humanProtein Serine-Threonine Kinases

Identifiers

PMID31160382
PMCPMC7302431
OpenAlexW2949507683

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.