Evidence map›Paper›PMID 31160362›Full record

ArticleInfection and immunity2019

Neisseria meningitidis Type IV Pili Trigger Ca

Simon Peters, Jan Schlegel, Jérôme Becam, Elita Avota, Markus Sauer, Alexandra Schubert-Unkmeir

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Interaction ofFrontiers in cellular and infection microbiology · 2024
    Article
  7. Article
  8. Article
  9. The Host-Pathogen Interactions and Epicellular Lifestyle ofFrontiers in cellular and infection microbiology · 2022
    Review
  10. Review
  11. Ceramide and Related Molecules in Viral Infections.International journal of molecular sciences · 2021
    Review
  12. Review
  13. Frontiers in microbiology · 2021
    Article
  14. Diverse Facets of Sphingolipid Involvement in Bacterial Infections.Frontiers in cell and developmental biology · 2019
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Simon PetersInstitute of Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
Jan SchlegelDepartment of Biotechnology and Biophysics, Biocenter, University of Wuerzburg, Wuerzburg, Germany.
Jérôme BecamInstitute of Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
Elita AvotaInstitute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Markus SauerDepartment of Biotechnology and Biophysics, Biocenter, University of Wuerzburg, Wuerzburg, Germany.
Alexandra Schubert-UnkmeirInstitute of Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany aunkmeir@hygiene.uni-wuerzburg.de.
University of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acid sphingomyelinase (ASM) is a lipid hydrolase that converts sphingomyelin to ceramide and that can be activated by various cellular stress mechanisms, including bacterial pathogens. Vesicle transportation or trafficking of ASM from the lysosomal compartment to the cell membrane is a prerequisite for its activation in response to bacterial infections; however, the effectors and mechanisms of ASM translocation and activation are poorly defined. Our recent work documented the key importance of ASM for

Indexed as

CalciumCells, CulturedCeramidesFimbriae, BacterialHumansLysosomesNeisseria meningitidisSphingomyelin PhosphodiesteraseCalciumCeramidesSphingomyelin Phosphodiesteraseacid sphingomyelinaseNeisseria meningitidissphingolipidssuperresolution microscopytype IV pili

Identifiers

PMID31160362
PMCPMC6652772
OpenAlexW2947747293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.