Evidence map›Paper›PMID 31160331›Full record

ArticleCancer discovery2019

Kinase Networks Regulate Metabolism: I'D(H1) Never Have Guessed!

Sarah Horton, Brian J P Huntly

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cancer discovery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sarah HortonWellcome Trust-MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom.
Brian J P HuntlyWellcome Trust-MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom. bjph2@cam.ac.uk.ORCID https://orcid.org/0000-0003-0312-161X
Wellcome/MRC Cambridge Stem Cell Institute · GB

Funding

Cancer Research UK 25508Medical Research Council MC_PC_12009Medical Research Council MR/R009708/1
6 · The paper itself

Abstract

Mutations in isoforms of isocitrate dehydrogenase (IDH) enzymes are described in multiple cancers and both mutant and wild-type IDH are important for the generation and maintenance of tumors, but how their activity is regulated is poorly understood. An article in this issue of

Indexed as

HumansIsocitrate DehydrogenaseMutationNeoplasmsProtein-Tyrosine KinasesIsocitrate DehydrogenaseProtein-Tyrosine Kinases

Identifiers

PMID31160331
OpenAlexW2947642437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.