Evidence map›Paper›PMID 31160300›Full record

ArticleBMJ case reports2019

Unexpected benefit from an 'old' metronomic chemotherapy regimen in advanced chordoma.

Mariella Spalato Ceruso, Andrea Napolitano, Marianna Silletta, Bruno Vincenzi

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mariella Spalato CerusoMedical Oncology, Universita Campus Bio-Medico di Roma, Roma, Lazio, Italy.
Andrea NapolitanoMedical Oncology, Universita Campus Bio-Medico di Roma, Roma, Lazio, Italy.ORCID http://orcid.org/0000-0002-7509-1555
Marianna SillettaMedical Oncology, Universita Campus Bio-Medico di Roma, Roma, Lazio, Italy.
Bruno VincenziMedical Oncology, Universita Campus Bio-Medico di Roma, Roma, Lazio, Italy.
Università Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this case report, we describe an older adult man affected by advanced chordoma progressing after treatment with cisplatin and imatinib. The patient was symptomatic for uncontrolled pain. We decided to treat the patient with metronomic cyclophosphamide, unexpectedly achieving long-lasting clinical and radiological benefit.

Indexed as

SacrumAdministration, MetronomicAgedAntineoplastic Combined Chemotherapy ProtocolsChordomaCyclophosphamideHumansMagnetic Resonance ImagingMaleNeoplasm Recurrence, LocalCyclophosphamidechemotherapygeriatric medicineoncology

Identifiers

PMID31160300
PMCPMC6557366
OpenAlexW2948638480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.