Evidence map›Paper›PMID 31160292›Full record

Trial reportAntimicrobial agents and chemotherapy2019

Intravenous Immunoglobulin Administration Significantly Increases BKPyV Genotype-Specific Neutralizing Antibody Titers in Kidney Transplant Recipients.

Aurélie Velay, Morgane Solis, Ilies Benotmane, Pierre Gantner, Eric Soulier, Bruno Moulin, Sophie Caillard, Samira Fafi-Kremer

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. BK virus nephropathy in a native kidney.Pediatric nephrology (Berlin, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. BK viral infection: A review of management and treatment.World journal of transplantation · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Aurélie VelayVirology Laboratory, Strasbourg University Hospital, Strasbourg, France.
Morgane SolisVirology Laboratory, Strasbourg University Hospital, Strasbourg, France.
Ilies BenotmaneStrasbourg University, INSERM, IRM UMR-S 1109, Strasbourg, France.
Pierre GantnerVirology Laboratory, Strasbourg University Hospital, Strasbourg, France.
Eric SoulierVirology Laboratory, Strasbourg University Hospital, Strasbourg, France.
Bruno MoulinStrasbourg University, INSERM, IRM UMR-S 1109, Strasbourg, France.
Sophie CaillardStrasbourg University, INSERM, IRM UMR-S 1109, Strasbourg, France.
Samira Fafi-KremerVirology Laboratory, Strasbourg University Hospital, Strasbourg, France samira.fafi-kremer@unistra.fr.
Inserm · FRUniversité de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) is one of the major causes of kidney graft dysfunction, and there are no BKPyV-specific antiviral therapies available. BKPyV neutralizing antibodies (NAbs) play key roles in protecting against BKPyV replication and represent a potential therapeutic or preventive strategy. In this study, we evaluated NAb titers in intravenous immunoglobulin (i.v. Ig) preparations and in kidney transplant recipients (KTR) before and after i.v. Ig administration. NAb titers directed against major BKPyV genotypes were measured using a BKPyV pseudovirion system. Thirty-three KTR receiving high (1 g/kg of body weight/day;

Indexed as

Kidney TransplantationAdolescentAdultAgedAntibodies, NeutralizingBK VirusFemaleGenotypeHumansImmunoglobulins, IntravenousImmunologic Deficiency SyndromesMaleMiddle AgedPolyomavirus InfectionsYoung AdultAntibodies, NeutralizingImmunoglobulins, IntravenousBK nephropathyBK virusintravenous immunoglobulinkidney transplantationviral infection

Identifiers

PMID31160292
PMCPMC6658761
OpenAlexW2948396358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.