Evidence map›Paper›PMID 31160291›Full record

ArticleAntimicrobial agents and chemotherapy2019

Unexpected Activity of Oral Fosfomycin against Resistant Strains of Escherichia coli in Murine Pyelonephritis.

Annabelle Pourbaix, François Guérin, Charles Burdet, Laurent Massias, Françoise Chau, Vincent Cattoir, Bruno Fantin

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Annabelle Pourbaix *INSERM, IAME, UMR 1137, Paris, France.
François Guérin *Université de Caen Normandie, EA 4655 (équipe Antibio-résistance), Caen, France.
Charles BurdetINSERM, IAME, UMR 1137, Paris, France.
Laurent MassiasINSERM, IAME, UMR 1137, Paris, France.
Françoise ChauINSERM, IAME, UMR 1137, Paris, France.
Vincent CattoirCHU de Rennes, Service de Bactériologie-Hygiène Hospitalière & CNR de la Résistance aux Antibiotiques, Rennes, France.ORCID 0000-0003-4026-9912
Bruno FantinINSERM, IAME, UMR 1137, Paris, France bruno.fantin@aphp.fr.ORCID 0000-0001-7904-9402
Inserm · FRCentre Hospitalier Universitaire de Caen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fosfomycin tromethamine activity is well established for oral treatment of uncomplicated lower urinary tract infections, but little is known about its potential efficacy in pyelonephritis. Ascending pyelonephritis was induced in mice infected with 6 strains of

Indexed as

Administration, OralAnimalsAnti-Bacterial AgentsEscherichia coliFemaleFosfomycinHumansHydrogen-Ion ConcentrationMiceMicrobial Sensitivity TestsPyelonephritisUrinary Tract InfectionsAnti-Bacterial AgentsFosfomycinantibiotic resistanceEscherichia colifosfomycinpyelonephritis

Identifiers

PMID31160291
PMCPMC6658801
OpenAlexW2950082551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.