Evidence map›Paper›PMID 31160286›Full record

ArticleAntimicrobial agents and chemotherapy2019

Reactive Oxygen Species Production Is a Major Factor Directing the Postantibiotic Effect of Fluoroquinolones in Streptococcus pneumoniae.

M T García, M V Valenzuela, M J Ferrándiz, A G de la Campa

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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  4. mBio · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

M T GarcíaDepartamento de Genética, Fisiología y Microbiología, Universidad Complutense, Madrid, Spain.
M V ValenzuelaDepartamento de Genética, Fisiología y Microbiología, Universidad Complutense, Madrid, Spain.
M J FerrándizUnidad de Genética Bacteriana, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain.
A G de la CampaUnidad de Genética Bacteriana, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain agcampa@isciii.es.
Universidad Complutense de Madrid · ESConsejo Superior de Investigaciones Científicas · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the molecular mechanisms involved in the postantibiotic effect of the fluoroquinolones levofloxacin and moxifloxacin in

Indexed as

DNA CleavageFluoroquinolonesLevofloxacinMicrobial Sensitivity TestsMoxifloxacinReactive Oxygen SpeciesStreptococcus pneumoniaeFluoroquinolonesLevofloxacinMoxifloxacinReactive Oxygen SpeciesDNA cleavagefluoroquinoloneslevofloxacinmoxifloxacinpostantibiotic effectreactive oxygen speciesStreptococcus pneumoniaetranscriptional regulation

Identifiers

PMID31160286
PMCPMC6658797
OpenAlexW2948011640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.