Evidence map›Paper›PMID 31160064›Full record

ArticleBritish journal of anaesthesia2019

Measurement of relative lung perfusion with electrical impedance and positron emission tomography: an experimental comparative study in pigs.

T Bluth, T Kiss, M Kircher, A Braune, C Bozsak, R Huhle, M Scharffenberg, M Herzog, J Roegner, P Herzog and 8 more

Registry-linked trialOpen access · bronzeAbstract readComparative Study
In one paragraph

Article in British journal of anaesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04776408 (Potential for Inhaled Nitric Oxide and Ventilation-Perfusion Mismatch by Electrical Impedance Tomography in the Acute Respiratory Distress Syndrome Patients With Lung Recruitment), which is not on this map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04776408 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Potential for Inhaled Nitric Oxide and Ventilation-Perfusion Mismatch by Electrical Impedance Tomography in the Acute Respiratory Distress Syndrome Patients With Lung Recruitment

TypeinterventionalSponsorFar Eastern Memorial HospitalRan2022 to 2024Enrolled100ConditionsNitric Oxide, Acute Respiratory Distress SyndromeArmsLung recruitment combined inhaled Nitric oxide, Lung recruitment
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 76 citations in OpenAlex.

  1. Enhancement of Pulmonary Function and Reduction of Complications Through EIT-Guided Yoga Breathing Exercise After Esophagectomy.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Trial
  2. Trial
  3. Observational
  4. Dead space in critical care: a practical approach with clinical scenarios.Journal of anesthesia, analgesia and critical care · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. [Research progress on electrical impedance tomography in pulmonary perfusion].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Review
  16. Article
  17. Review
  18. Regional lung perfusion using different indicators in electrical impedance tomography.Journal of applied physiology (Bethesda, Md. : 1985) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

T BluthPulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
T KissPulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
M KircherInstitute of Biomedical Engineering, Karlsruhe Institute of Technology, Karlsruhe, Germany.
A BraunePulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
C BozsakDrägerwerk AG & Co. KGaA, Lübeck, Germany.
R HuhlePulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
M ScharffenbergPulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
M HerzogPulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
J RoegnerPulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
P HerzogPulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
L VivonaPulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, Italy.
M MillonePulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; IRCCS AOU San Martino IST, Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.
O DösselInstitute of Biomedical Engineering, Karlsruhe Institute of Technology, Karlsruhe, Germany.
M AndreeffDepartment of Nuclear Medicine, University Hospital Carl Gustav Carus, Dresden, Germany.
T KochPulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
J KotzerkeDepartment of Nuclear Medicine, University Hospital Carl Gustav Carus, Dresden, Germany.
B StenderDrägerwerk AG & Co. KGaA, Lübeck, Germany.
M Gama de AbreuPulmonary Engineering Group Dresden, Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. Electronic address: mgabreu@uniklinikum-dresden.de.
University Hospital Carl Gustav Carus · DEDräger (Germany) · DEKarlsruhe Institute of Technology · DEOspedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElectrical impedance tomography (EIT) with indicator dilution may be clinically useful to measure relative lung perfusion, but there is limited information on the performance of this technique.

methodsThirteen pigs (50-66 kg) were anaesthetised and mechanically ventilated. Sequential changes in ventilation were made: (i) right-lung ventilation with left-lung collapse, (ii) two-lung ventilation with optimised PEEP, (iii) two-lung ventilation with zero PEEP after saline lung lavage, (iv) two-lung ventilation with maximum PEEP (20/25 cm H

resultsDifferences between methods were relatively small (95% of values differed by less than 8.7%, 8.9%, and 9.5% for saline 10%, 5%, and 3%, respectively). Compared with PET, EIT underestimated relative perfusion in dependent, and overestimated it in non-dependent, regions. EIT and PET detected the same direction of change in relative lung perfusion in 68.9-95.9% of measurements.

conclusionsThe agreement between EIT and PET for measuring and tracking changes of relative lung perfusion was satisfactory for clinical purposes. Indicator-based EIT may prove useful for measuring pulmonary perfusion at bedside.

Indexed as

Positron-Emission TomographyRespiration, ArtificialAnimalsDisease Models, AnimalElectric ImpedanceLungPulmonary VentilationSwineelectrical impedance tomographyindicator dilutionpositron emission tomographyregional pulmonary perfusion

Identifiers

PMID31160064
PMCPMC6676171
OpenAlexW2947836307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.