Evidence map›Paper›PMID 31159757›Full record

SynthesisBMC public health2019

Prevalence of hepatitis G virus infection among 67,348 blood donors in mainland China.

Taiwu Wang, Juecai Chen, Qi Zhang, Xia Huang, Nanzhen Xie, Jinhai Zhang, Tongjian Cai, Yao Zhang, Hongyan Xiong

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Taiwu WangDepartment of Epidemiology, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, People's Republic of China.
Juecai ChenThe First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People's Republic of China.
Qi ZhangCenter for Disease Control and Prevention of Eastern Theater Command, Nanjing, 210002, People's Republic of China.
Xia HuangChongqing Blood Center, Chongqing, 400015, People's Republic of China.
Nanzhen XieChongqing General Hospital, Chongqing, 400013, People's Republic of China.
Jinhai ZhangCenter for Disease Control and Prevention of Eastern Theater Command, Nanjing, 210002, People's Republic of China.
Tongjian CaiDepartment of Epidemiology, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, People's Republic of China.
Yao ZhangDepartment of Epidemiology, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, People's Republic of China. sydzy2003@sina.com.
Hongyan XiongDepartment of Epidemiology, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, People's Republic of China. hongyanxiong@126.com.
Army Medical University · CNFirst Affiliated Hospital of Chengdu Medical College · CNFirst People's Hospital of Chongqing · CN

Funding

Chongqing Health and Family Planning Commission 20141027National Natural Science Foundation of China 81202220Natural Science Foundation of Jiangsu Province BK20150094
6 · The paper itself

Abstract

backgroundHepatitis G virus (HGV) infection transmitted from blood donors is a concern in China, as many articles about HGV infection in Chinese blood donors from different provinces have been published. This study aimed to evaluate the overall prevalence of HGV infection in Chinese blood donors and analyse the potential risk of HGV infection through blood transfusion in China.

methodsWe performed a literature search in PubMed, EMBASE, Web of Science, the Chinese BioMedical Literature Database (CBM) and the China National Knowledge Infrastructure (CNKI) up to October 2018 regarding the prevalence of HGV in Chinese blood donors. Eligibility assessment and data extraction were conducted independently by 2 researchers, and meta-analysis was performed to synthesize the data. Heterogeneity was evaluated using Cochran's Q test and quantified using the I

resultsA total of 102 studies with 67,348 blood donors published from 1996 to 2016 and covering 26 provinces or municipalities were included for further analyses. The pooled prevalence of HGV was 3.91% (95%CI: 3.18-4.71%) by enzyme immune assay/enzyme linked immunosorbent assay (EIA/ELISA) and 3.25% (95%CI: 2.35-4.26%) by polymerase chain reaction (PCR). The prevalence of HGV may be significantly affected by region, province or municipality and potentially by the paid/voluntary status of the blood donors. No significant difference was found between plasma and full blood donation.

conclusionsThe prevalence of HGV in blood donors from China was similar to that in blood donors from many other countries and higher than that of some other hepatitis viruses, such as hepatitis B virus. The risk of transfusion-transmitted HGV still exists after routine blood donor screening, especially in those patients coinfected with other hepatitis viruses and/or HIV. On the basis of our study, we may suggest adding HGV screening for blood transfusions in mainland China in the future.

Indexed as

Blood DonorsBlood TransfusionGB virus CAdultChinaEnzyme-Linked Immunosorbent AssayFemaleFlaviviridaeHepatitis, Viral, HumanHumansMaleMass ScreeningMiddle AgedPolymerase Chain ReactionPrevalenceRisk FactorsRNA, Viral

Identifiers

PMID31159757
PMCPMC6547458
OpenAlexW2948806819

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.