Evidence map›Paper›PMID 31159406›Full record

ArticleDiagnostics (Basel, Switzerland)2019

Detecting Synchronous Thyroid Adenoma and False-Positive Findings on Technetium-99m MIBI Single Photon-Emission Computed Tomography/Computed Tomography.

Ji Young Lee, Hee-Sung Song, Jae Hyuck Choi, Chang Lim Hyun, Sang Ah Lee, Joon-Hyouk Choi, Seokjae Lee

Open access · goldAbstract readCase Reports
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ji Young LeeDepartment of Nuclear Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju-si 63241, Korea. easy02000@naver.com.
Hee-Sung SongDepartment of Nuclear Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju-si 63241, Korea. heesung119@gmail.com.ORCID 0000-0003-3891-8848
Jae Hyuck ChoiDepartment of Surgery, Jeju National University Hospital, Jeju National University School of Medicine, Jeju-si 63241, Korea. basson@hanmail.net.
Chang Lim HyunDepartment of Pathology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju-si 63241, Korea. venisua@jejunu.ac.kr.
Sang Ah LeeDepartment of Endocrinology and Metabolism, Jeju National University Hospital, Jeju National University School of Medicine, Jeju-si 63241, Korea. sahe7@hanmail.net.
Joon-Hyouk ChoiDepartment of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju-si 63241, Korea. valgom@hanmail.net.
Seokjae LeeJeju National University College of Medicine and Graduate School of Medicine, Jeju-si 63241, Korea. Lsjtop@gmail.com.
Jeju National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Technetium (Tc)-99m-methoxyisobutylisonitrile (MIBI) single photon-emission computed tomography/computed tomography (SPECT/CT) is now being used increasingly for preoperative localization of parathyroid adenomas. Tc-99m-MIBI scintigraphy in a 52-year-old man with a diagnosis of primary hyperparathyroidism revealed two focal areas with retention of radioactivity in the left lobe of the thyroid gland on the delayed phase of MIBI SPECT/CT but no significant focal radioactive uptake on MIBI planar images. The patient subsequently underwent left partial parathyroidectomy. Histological analysis identified one lesion to be thyroid hyperplasia and the other to be parathyroid adenoma. This case demonstrates the value of MIBI SPECT/CT for localization of a parathyroid lesion when compared with planar images and that false-positive findings can lead to misdiagnosis in a patient with coexisting thyroid disease. An appropriate diagnostic work-up that includes Tc-99m MIBI SPECT/CT in addition to ultrasonography is helpful for an accurate diagnosis in patients with concomitant thyroid disease.

Indexed as

false-positive findingparathyroid adenomaprimary hyperparathyroidismTc-99m MIBI scintigraphyTc-99m MIBI SPECT/CT

Identifiers

PMID31159406
PMCPMC6627855
OpenAlexW2947819121

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.