Evidence map›Paper›PMID 31159357›Full record

ReviewMarine drugs2019

Sea Anemone Toxins: A Structural Overview.

Bruno Madio, Glenn F King, Eivind A B Undheim

Abstract readReview
In one paragraph

Review in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
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  11. Review
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  15. Voltage-Gated KMarine drugs · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Isolation and cDNA cloning of four peptide toxins from the sea anemoneThe journal of venomous animals and toxins including tropical diseases · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bruno MadioInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia. b.madio@uq.edu.au.
Glenn F KingInstitute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia. glenn.king@imb.uq.edu.au.ORCID 0000-0002-2308-2200
Eivind A B UndheimCentre for Advanced Imaging, The University of Queensland, St. Lucia, QLD 4072, Australia. e.undheim@uq.edu.au.

Funding

Australian National Health & Medical Research Council APP1136889Australian Research Council DE160101142
6 · The paper itself

Abstract

Sea anemones produce venoms of exceptional molecular diversity, with at least 17 different molecular scaffolds reported to date. These venom components have traditionally been classified according to pharmacological activity and amino acid sequence. However, this classification system suffers from vulnerabilities due to functional convergence and functional promiscuity. Furthermore, for most known sea anemone toxins, the exact receptors they target are either unknown, or at best incomplete. In this review, we first provide an overview of the sea anemone venom system and then focus on the venom components. We have organised the venom components by distinguishing firstly between proteins and non-proteinaceous compounds, secondly between enzymes and other proteins without enzymatic activity, then according to the structural scaffold, and finally according to molecular target.

Indexed as

AnimalsCnidarian VenomsMarine ToxinsModels, MolecularSea AnemonesCnidarian VenomsMarine Toxinscytotoxinenzymemolecular scaffoldneurotoxinsea anemonetoxinvenom

Identifiers

PMID31159357
PMCPMC6627431

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.