Evidence map›Paper›PMID 31159348›Full record

ReviewInternational journal of molecular sciences2019

Microbiota: Overview and Implication in Immunotherapy-Based Cancer Treatments.

Giovanni Brandi, Giorgio Frega

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Subtype-Based Microbial Analysis in Non-small Cell Lung Cancer.Tuberculosis and respiratory diseases · 2023
    Article
  5. Review
  6. Review
  7. Article
  8. Advances in molecular mechanisms of interaction betweenTranslational lung cancer research · 2021
    Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Giovanni BrandiDepartment of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, 40138, Bologna, Italy. giovanni.brandi@unibo.it.
Giorgio FregaDepartment of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, 40138, Bologna, Italy. giorgio.frega2@unibo.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last few years, the gut microbiota has gained increasing attention as a consequence of its emerging role as a modulator of the immune system. With the advent of the era of checkpoint inhibitors immunotherapy and adoptive cell transfer (ACT) in oncology, these findings became of primary relevance in light of experimental data that suggested the microbiota involvement as a plausible predictor of a good or poor response. These remarks justify the efforts to pinpoint the specific actions of the microbiota and to identify new strategies to favorably edit its composition.

Indexed as

ImmunotherapyMicrobiotaAnimalsBiomarkers, TumorGastrointestinal MicrobiomeHumansImmunotherapy, AdoptiveNeoplasmsT-LymphocytesT-Lymphocyte SubsetsBiomarkers, Tumoradoptive cell transfer (ACT)cancerCAR T-cellcheckpoint inhibitorsdietimmuno-oncologyimmunotherapymicrobiomemicrobiotaTCRTIL

Identifiers

PMID31159348
PMCPMC6600175

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.