Evidence map›Paper›PMID 31159259›Full record

ArticleGenes2019

Engineering CatM, a LysR-Type Transcriptional Regulator, to Respond Synergistically to Two Effectors.

Melissa P Tumen-Velasquez, Nicole S Laniohan, Cory Momany, Ellen L Neidle

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Regulation of tricarboxylate transport and metabolism inApplied and environmental microbiology · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Melissa P Tumen-VelasquezDepartments of Microbiology, University of Georgia, Athens, GA 30602, USA. dnavgais@uga.edu.
Nicole S LaniohanDepartments of Microbiology, University of Georgia, Athens, GA 30602, USA. nlanio@uga.edu.
Cory MomanyDepartments of Microbiology, University of Georgia, Athens, GA 30602, USA. cmomany@uga.edu.
Ellen L NeidleDepartments of Microbiology, University of Georgia, Athens, GA 30602, USA. eneidle@uga.edu.ORCID 0000-0003-1665-5303
University of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The simultaneous response of one transcriptional regulator to different effectors remains largely unexplored. Nevertheless, such interactions can substantially impact gene expression by rapidly integrating cellular signals and by expanding the range of transcriptional responses. In this study, similarities between paralogs were exploited to engineer novel responses in CatM, a regulator that controls benzoate degradation in

Indexed as

AcinetobacterBacterial ProteinsDNA-Binding ProteinsOrganic Cation Transport ProteinsRegulatory Elements, TranscriptionalTranscription FactorsBacterial ProteinsBenM protein, AcinetobactercatM protein, AcinetobacterDNA-Binding ProteinsLysR protein, BacteriaOrganic Cation Transport ProteinsTranscription FactorsAcinetobacterbenzoatebiosensorLTTRLysRmuconatesynergismtranscription factor

Identifiers

PMID31159259
PMCPMC6628147
OpenAlexW2947129383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.