Evidence map›Paper›PMID 31159241›Full record

ArticleNanomaterials (Basel, Switzerland)2019

"Three-Bullets" Loaded Mesoporous Silica Nanoparticles for Combined Photo/Chemotherapy.

André Luiz Tessaro, Aurore Fraix, Ana Claudia Pedrozo da Silva, Elena Gazzano, Chiara Riganti, Salvatore Sortino

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

André Luiz TessaroLaboratory of Photochemistry, Department of Drug Sciences, University of Catania, 95125 Catania, Italy. andretessaro@utfpr.edu.br.
Aurore FraixLaboratory of Photochemistry, Department of Drug Sciences, University of Catania, 95125 Catania, Italy. fraix@unict.it.ORCID 0000-0002-8328-3290
Ana Claudia Pedrozo da SilvaDepartment of Chemistry, Universidade Estadual de Maringá, Av. Colombo, 5.790, Maringá 87.020-900, Paraná, Brazil. anapedrozo1@gmail.com.
Elena GazzanoDepartment of Oncology, University of Torino, Via Santena 5/bis, I-10126 Torino, Italy. elena.gazzano@unito.it.ORCID 0000-0003-0939-0562
Chiara RigantiDepartment of Oncology, University of Torino, Via Santena 5/bis, I-10126 Torino, Italy. chiara.riganti@unito.it.ORCID 0000-0001-9787-4836
Salvatore SortinoLaboratory of Photochemistry, Department of Drug Sciences, University of Catania, 95125 Catania, Italy. ssortino@unict.it.
University of Catania · ITUniversity of Turin · ITUniversidade Estadual de Maringá · BRUniversidade Tecnológica Federal do Paraná · BR

Funding

Associazione Italiana per la Ricerca sul Cancro IG-19859
6 · The paper itself

Abstract

This contribution reports the design, preparation, photophysical and photochemical characterization, as well as a preliminary biological evaluation of mesoporous silica nanoparticles (MSNs) covalently integrating a nitric oxide (NO) photodonor (NOPD) and a singlet oxygen (

Indexed as

doxorubicinmultimodal therapynitric oxidesinglet oxygen

Identifiers

PMID31159241
PMCPMC6631764
OpenAlexW2947039950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.