Evidence map›Paper›PMID 31159179›Full record

ReviewNutrients2019

Towards a Food Pharmacy: Immunologic Modulation through Diet.

Ilse Molendijk, Sander van der Marel, P W Jeroen Maljaars

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Synthetic and systems biotechnology · 2027
    Review
  5. Dietary Patterns and Food Choices of Adults With Inflammatory Bowel Disease in New Zealand.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Article
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  19. The Influence of Nutrients on Inflammatory Bowel Diseases.Journal of nutrition and metabolism · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ilse MolendijkDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, 2313 ZA Leiden, The Netherlands. i.molendijk@lumc.nl.
Sander van der MarelDepartment of Gastroenterology and Hepatology, Haaglanden Medical Center, 2512 VA The Hague, The Netherlands. s.van.der.marel@haaglandenmc.nl.
P W Jeroen MaljaarsDepartment of Gastroenterology and Hepatology, Leiden University Medical Center, 2313 ZA Leiden, The Netherlands. p.w.j.maljaars@lumc.nl.ORCID 0000-0003-0477-9499
Leiden University Medical Center · NLMedisch Centrum Haaglanden · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients frequently wonder whether their dietary pattern influences the course of inflammatory bowel disease (IBD). Many patients even avoid certain foods that aggravate their symptoms. Although interest in nutritional interventions is rising among physicians, the current application of nutritional interventions in the IBD population is limited due to the lack of scientific evidence from clinical trials. Several studies, however, have identified associations between diet, gut microbiota, intestinal epithelial integrity, and mucosal immune responses. In patients consuming predominantly a Western diet high in n-6 poly-unsaturated fatty acids (PUFAs), sugars, and meat, and low in fruits and vegetables, an impaired gut epithelial barrier and disturbances in the intestinal microbiota have been observed, resulting in a chronic mucosal inflammation. An anti-inflammatory diet may restore this disbalance. In this review, we discuss the effects of diet on the composition of the microbiota, the gut epithelial barrier function, and the mucosal immune system.

Indexed as

Gastrointestinal MicrobiomeDiet, WesternFoodHumansInflammatory Bowel Diseasesdietary modificationexclusive enteral nutritioninflammatory bowel diseaselifestyle modificationMediterranean diet

Identifiers

PMID31159179
PMCPMC6627620
OpenAlexW2947919732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.