Evidence map›Paper›PMID 31158952›Full record

ArticleGut and liver2020

Ashwin D Dhanda, Euan Yates, Lauren P Schewitz-Bowers, Philippa J Lait, Richard W J Lee, Matthew E Cramp

Abstract readEvaluation Study
In one paragraph

Article in Gut and liver, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Oxidative stress in alcohol-related liver disease.World journal of hepatology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashwin D DhandaSouth West Liver Unit, University Hospitals Plymouth NHS Trust, Plymouth, UK.ORCID 0000-0002-0523-0193
Euan YatesHepatology Research Group, University of Plymouth, Plymouth, UK.ORCID 0000-0003-3082-2972
Lauren P Schewitz-BowersTranslational Health Sciences, University of Bristol, Bristol, UK.ORCID 0000-0001-6559-2228
Philippa J LaitTranslational Health Sciences, University of Bristol, Bristol, UK.ORCID 0000-0001-9454-8824
Richard W J LeeTranslational Health Sciences, University of Bristol, Bristol, UK.ORCID 0000-0002-9480-6843
Matthew E CrampSouth West Liver Unit, University Hospitals Plymouth NHS Trust, Plymouth, UK.ORCID 0000-0002-1152-0568

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcoholic hepatitis (AH) is an acute inflammatory liver condition with high early mortality rate. Steroids improve short-term survival but nonresponders have the worst outcomes. There is a clinical need to identify these high-risk individuals at the time of presentation. T cells are implicated in AH and steroid responsiveness. We measured

Indexed as

BiomarkersCytokinesFemaleHepatitis, AlcoholicHumansInterferon-gammaInterleukin-10Interleukin-17MaleMiddle AgedPredictive Value of TestsRisk AssessmentSteroidsSurvival AnalysisT-LymphocytesTreatment OutcomeBiomarkersCytokinesIL10 protein, humanIL17A protein, humanInterferon-gammaInterleukin-10Interleukin-17SteroidsTumor Necrosis Factor-alphaBiomarkerCytokinesHepatitis, alcoholicT cells

Identifiers

PMID31158952
PMCPMC7096227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.