Evidence map›Paper›PMID 31158438›Full record

ArticleNeuroscience2019

Coevolution of Residues Provides Evidence of a Functional Heterodimer of 5-HT

Bernard Fongang, Kathryn A Cunningham, Maga Rowicka, Andrzej Kudlicki

Open access · greenAbstract read
In one paragraph

Article in Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The 5-HT and PLC Signaling Pathways Regulate the Secretion of IL-1Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bernard FongangDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UTHSCSA, San Antonio, TX 78229, USA; Department of Biochemistry and Structural Biology, UTHSCSA, San Antonio, TX 78229, USA; Department of Epidemiology and Biostatistics, UTHSCSA, San Antonio, TX 78229, USA. Electronic address: fongang@uthscsa.edu.
Kathryn A CunninghamCenter for Addiction Research and Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Maga RowickaDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA; Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.
Andrzej KudlickiDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX 77555, USA; Sealy Center for Molecular Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA. Electronic address: askudlic@utmb.edu.
The University of Texas Medical Branch at Galveston · US

Funding

UTMB Clinical and Translational Science AwardUL1TR000071 · NCATS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BRASIER, ALLAN R. · 2012 to 2014
$14.4M
Translational Addiction Sciences CenterP50DA033935 · NIDA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CUNNINGHAM, KATHRYN A. · 2013 to 2017
$6.7M
Decoding Genome Instability by Combining Accurate Mapping and Predictive ModelingR01GM112131 · NIGMS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI ROWICKA, MAGA MALGORZATA · 2014 to 2023
$3.2M
NCATS NIH HHS UL1 TR000071NIDA NIH HHS P50 DA033935NIGMS NIH HHS R01 GM112131
6 · The paper itself

Abstract

Serotonin is a neurotransmitter that plays a role in regulating activities such as sleep, appetite, mood and substance abuse disorders; serotonin receptors 5-HT

Indexed as

AnimalsDatabases, GeneticEvolution, MolecularPapio anubisPhosphorylationReceptor, Serotonin, 5-HT2AReceptor, Serotonin, 5-HT2CTranscriptomeReceptor, Serotonin, 5-HT2AReceptor, Serotonin, 5-HT2C5-HT(2A) receptor5-HT(2C) receptordirect coupling analysisevolutionary couplingGaussian convolutionserotonin receptors

Identifiers

PMID31158438
PMCPMC7299066
OpenAlexW2947297198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.