Observational studyPsychological science2019
Perceived Weight Discrimination Mediates the Prospective Association Between Obesity and Physiological Dysregulation: Evidence From a Population-Based Cohort.
Observational study in Psychological science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Weight and Procedural Abortion Complications: A Systematic Review.Obstetrics and gynecology · 2025Pooled it
- Internalised weight stigma as a mediator of the relationship between experienced/perceived weight stigma and biopsychosocial outcomes: a systematic review.International journal of obesity (2005) · 2022Pooled it
- A randomized controlled trial of an acceptance and commitment therapy-informed diabetes prevention program reduces body shame and distress.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025Trial
- Nutrition Care and Dietetic Practice in Managing Metabolic and Endocrine Dysfunction in Polyendocrine Metabolic Ovarian Syndrome (PMOS): Implications and Opportunities in the Context of the Name Change of Polycystic Ovarian Syndrome to PMOS.Advances in nutrition (Bethesda, Md.) · 2026Review
- Weight discrimination and metabolic syndrome: Examining discrimination attributions and frequency across settings.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Understanding the Relationship Between Weight Discrimination and Cardiometabolic Risk Factors in Diabetes: Findings from the English Longitudinal Study of Ageing (ELSA).International journal of behavioral medicine · 2026Article
- Development and validation of the EDIT weight stigma reduction checklist.International journal of obesity (2005) · 2026Article
- Internalized weight stigma, metabolic syndrome, and inflammation in postmenopausal women with obesity.Brain, behavior, & immunity - health · 2025Article
- The legality of weight discrimination in Canada: an environmental scan of case law and the limits of Canadian legislation.International journal for equity in health · 2025Review
- Disentangling consequences of self-perceived weight from excess adiposity in metabolically healthy overweight/obesity.BMC public health · 2025Observational
- Weight stigma amid pediatric healthcare providers: a cross-sectional survey study assessing the roles of weight controllability beliefs and blame.BMC pediatrics · 2025Article
- Exploring the Role of Intrinsic Motivation in Healthy Eating Intentions: An Extension of the Theory of Planned Behavior in Chinese Adults.Nutrients · 2025Article
- Impacts of stigma and discrimination on people with obesity who smoke cigarettes.Addictive behaviors reports · 2025Article
- Factors that influence general practitioners' obesity-related clinical practices and determinants of behavior to target to promote best practice in obesity care: A qualitative exploration.Obesity science & practice · 2024Article
- Comparison between grip strength and relative grip strength in their relationship with allostatic load among adolescents.BMC public health · 2024Article
- Obesity, psychological well-being related measures, and risk of seven non-communicable diseases: evidence from longitudinal studies of UK and US older adults.International journal of obesity (2005) · 2024Article
- Lifetime and Daily Weight Stigma among Higher Weight Sexual Minority Women: Links to Daily Weight-based Concerns, Avoidance, and Negative Affect.Stigma and health · 2024Article
- 'Beyond the Scale': A Qualitative Exploration of the Impact of Weight Stigma Experienced by Patients With Obesity in General Practice.Health expectations : an international journal of public participation in health care and health policy · 2024Article
- Article
- Raising awareness of anti-fat stigma in healthcare through lived experience education: a continuing professional development pilot study.BMC medical education · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
Abstract
Obesity is thought to cause ill health because of the biological strain that excess fat has on physiological function. We tested an alternative explanation in a population-based sample of 3,609 older English adults-that the pervasive discrimination experienced by individuals with excess weight may in part explain why obesity is associated with subsequent multisystem physiological dysregulation, measured via clinical indicators of cardiovascular, metabolic, and immune function. We found that both obesity and perceived weight discrimination predicted an increase in physiological dysregulation from baseline to follow-up 4 years later. Perceived discrimination because of body weight experienced by individuals with obesity explained more than one quarter of the prospective association between obesity and a deterioration in biomarkers of health status. These findings highlight the possibility that the stigma experienced by individuals with obesity may play an important role in explaining the obesity-related disease burden.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.